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Gene

ACVR1B

activin A receptor type 1B

Summary

Cytogenetic location
12q13.13
Coordinates
Chromosome 12: 51,951,699–51,997,078 (GRCh38)
Exons
9 exons across 45.4 kb
Protein
505 amino acids
Also known as
ALK4, SKR2, ActRIB
Previous symbols
ACVRLK4
MANE Select transcript
ENST00000257963.9NM_004302.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ACVR1B yet. The test sequences your whole genome, so your data includes it all the same.

How ACVR1B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where ACVR1B sits. ACVR1B and 21 genes near it on chromosome 12, from 51,474,389 to 52,474,388.Chromosome 1212q13.13p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3351.6 Mb51.8 Mb52 Mb52.2 Mb52.4 MbSLC4A8: 51,391,317–51,515,763, forward strandSLC4A8SCN8A: 51,590,266–51,812,864, forward strandSCN8ATMDD1: 51,813,921–51,814,925, reverse strandTMDD1FIGNL2: 51,817,899–51,848,729, reverse strandFIGNL2ANKRD33: 51,888,009–51,891,727, forward strandANKRD33ACVRL1: 51,906,908–51,923,361, forward strandACVRL1ACVR1B: 51,951,699–51,997,078, forward strandACVR1BTAMALIN: 52,006,941–52,015,893, forward strandTAMALINNR4A1: 52,022,832–52,059,509, forward strandNR4A1ATG101: 52,069,246–52,077,495, forward strandATG101SMIM41: 52,079,704–52,108,255, forward strandSMIM41KRT80: 52,168,996–52,192,311, reverse strandKRT80KRT7: 52,232,520–52,252,186, forward strandKRT7KRT86: 52,249,300–52,309,163, forward strandKRT86KRT81: 52,285,913–52,291,534, reverse strandKRT81KRT83: 52,314,301–52,321,398, reverse strandKRT83KRT85: 52,360,006–52,367,481, reverse strandKRT85KRT84: 52,377,812–52,385,652, reverse strandKRT84KRT82: 52,393,931–52,406,335, reverse strandKRT82KRT75: 52,424,070–52,434,380, reverse strandKRT75KRT6B: 52,446,651–52,452,154, reverse strandKRT6BKRT6C: 52,468,516–52,473,805, reverse strandKRT6CDiagram of ACVR1B: 9 exons on the forward strand of chromosome 12Exon 1: 51,951,699–51,951,834, 136 basesExon 2: 51,975,265–51,975,504, 240 basesExon 3: 51,976,327–51,976,575, 249 basesExon 4: 51,980,969–51,981,199, 231 basesExon 5: 51,983,999–51,984,166, 168 basesExon 6: 51,985,192–51,985,348, 157 basesExon 7: 51,986,818–51,986,942, 125 basesExon 8: 51,991,863–51,991,993, 131 basesExon 9: 51,993,985–51,997,078, 3,094 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.5 kb of the gene's 45.4 kb; 1,518 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). ACVR1B gene: activin A receptor type 1B. Retrieved 17 October 2026, from https://dantelabs.com/genes/acvr1b

Vancouver

Dante Labs. ACVR1B gene: activin A receptor type 1B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/acvr1b

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