Progressive narrowing of the arteries at the base of the brain, linked to changes in RNF213 (a susceptibility gene with reduced penetrance, especially common in East Asian populations), ACTA2 or GUCY1A1, which can cause strokes or mini-strokes.
What a diagnosis changes
Knowing about it supports early assessment of symptoms such as transient weakness, and access to specialist stroke prevention and surgical treatment.
Also known as
idiopathic Moyamoya disease; Moyamoya disease, primary; Moyamoya disease, secondary; MYMY; progressive intracranial arterial occlusion
Includes 8 related subtypes ↓Hide subtypes ↑
- moyamoya angiopathy-short stature-facial dysmorphism-hypergonadotropic hypogonadism syndrome
- moyamoya disease 1
- Moyamoya disease 2
- moyamoya disease 3
- Moyamoya disease 5
- moyamoya disease 7
- Moyamoya disease 8
- Moyamoya disease with early-onset achalasia
