Trait
Spotty increased pigmentation
Clinical name: Spotty hyperpigmentation
Summary
- Also called
- Patchy hyperpigmentation
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
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Get my Genome Test9 genes linked to Spotty increased pigmentation
Changes in these genes cause rare conditions in which Spotty increased pigmentation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| BANF1barrier to autointegration nuclear assembly factor 1 | Always | In 1 condition |
| KRT14keratin 14 | Often (30–79%) | In 1 condition |
| KRT5keratin 5 | Often (30–79%) | In 2 conditions |
| PDE11Aphosphodiesterase 11A | Often (30–79%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Often (30–79%) | In 1 condition |
| SRD5A3steroid 5 alpha-reductase 3 | Sometimes (5–29%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Rarely (1–4%) | In 1 condition |
| CRIPTCXXC repeat containing interactor of PDZ3 domain | Not recorded | In 1 condition |
| FERMT1FERM domain containing kindlin 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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