Trait
Progressive flexion contractures
Progressively worsening joint contractures.
Summary
- Also called
- Joint contractures, progressive
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
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Get my Genome Test7 genes linked to Progressive flexion contractures
Changes in these genes cause rare conditions in which Progressive flexion contractures is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ANTXR2ANTXR cell adhesion molecule 2 | Sometimes (5–29%) | In 2 conditions |
| ESCO2establishment of sister chromatid cohesion N-acetyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| GCH1GTP cyclohydrolase 1 | Sometimes (5–29%) | In 1 condition |
| IMPDH2inosine monophosphate dehydrogenase 2 | Sometimes (5–29%) | In 1 condition |
| MED12mediator complex subunit 12 | Sometimes (5–29%) | In 1 condition |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Sometimes (5–29%) | In 1 condition |
| SYT1synaptotagmin 1 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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