Trait

Lambdoidal craniosynostosis

A kind of craniosynostosis affecting the lambdoidal suture.

Also called: Lambdoid suture craniosynostosis, Lambdoid suture synostosis
Body system: Abnormality of head or neck Abnormality of the musculoskeletal system

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17 condition reports read genes linked to this trait

Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.

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17 genes linked to Lambdoidal craniosynostosis

Changes in these genes cause rare conditions in which Lambdoidal craniosynostosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
AHDC1AT-hook DNA binding motif containing 1	Always	In 1 condition
ERFETS2 repressor factor	Often (30–79%)	In 1 condition
FGFR2fibroblast growth factor receptor 2	Often (30–79%)	In 4 conditions
IL11RAinterleukin 11 receptor subunit alpha	Often (30–79%)	In 1 condition
PIGTphosphatidylinositol glycan anchor biosynthesis class T	Often (30–79%)	In 1 condition
RNU12RNA, U12 small nuclear	Often (30–79%)	In 1 condition
HNRNPKheterogeneous nuclear ribonucleoprotein K	Sometimes (5–29%)	In 2 conditions
RECQL4RecQ like helicase 4	Sometimes (5–29%)	In 1 condition
SLC4A10solute carrier family 4 member 10	Sometimes (5–29%)	In 1 condition
TCOF1treacle ribosome biogenesis factor 1	Sometimes (5–29%)	In 1 condition
ZIC1Zic family zinc finger 1	Sometimes (5–29%)	In 1 condition
BMP4bone morphogenetic protein 4	Not recorded	In 1 condition
MASP1MBL associated serine protease 1	Not recorded	In 1 condition
PORcytochrome p450 oxidoreductase	Not recorded	In 1 condition
RAB23RAB23, member RAS oncogene family	Not recorded	In 1 condition
SEC24DSEC24 homolog D, COPII component	Not recorded	In 1 condition
TWIST1twist family bHLH transcription factor 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Unilambdoid synostosis1 gene

Broader traits

Deformity of the skull

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.19-9814e911.

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