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Gene

GUF1

GTP binding elongation factor GUF1

Summary

Cytogenetic location
4p12
Coordinates
Chromosome 4: 44,678,420–44,700,928 (GRCh38)
Exons
17 exons across 22.5 kb
Protein
669 amino acids
Also known as
FLJ13220
MANE Select transcript
ENST00000281543.6NM_021927.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GUF1 yet. The test sequences your whole genome, so your data includes it all the same.

How GUF1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 4, with a bracket where GUF1 sits. GUF1 and 3 genes near it on chromosome 4, from 44,189,674 to 45,189,673.Chromosome 44p12p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.244.2 Mb44.4 Mb44.6 Mb44.8 Mb45 MbKCTD8: 44,173,903–44,448,930, reverse strandKCTD8YIPF7: 44,622,088–44,678,795, reverse strandYIPF7GUF1: 44,678,420–44,700,928, forward strandGUF1GNPDA2: 44,682,200–44,726,621, reverse strandGNPDA2Diagram of GUF1: 17 exons on the forward strand of chromosome 4Exon 12: 2 known disease-causing sitesExon 1: 44,678,420–44,678,787, 368 basesExon 2: 44,680,441–44,680,552, 112 basesExon 3: 44,680,694–44,680,842, 149 basesExon 4: 44,681,123–44,681,203, 81 basesExon 5: 44,682,334–44,682,411, 78 basesExon 6: 44,683,235–44,683,318, 84 basesExon 7: 44,685,959–44,686,023, 65 basesExon 8: 44,686,510–44,686,713, 204 basesExon 9: 44,688,007–44,688,146, 140 basesExon 10: 44,689,286–44,689,409, 124 basesExon 11: 44,689,843–44,689,975, 133 basesExon 12: 44,690,717–44,690,860, 144 basesExon 13: 44,691,666–44,691,799, 134 basesExon 14: 44,694,412–44,694,513, 102 basesExon 15: 44,695,615–44,695,734, 120 basesExon 16: 44,697,408–44,697,444, 37 basesExon 17: 44,698,544–44,700,928, 2,385 bases1246810121416175′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.5 kb of the gene's 22.5 kb; 2,010 of those bases code for the protein.

How a genome test reads GUF1

2

positions in GUF1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 22.5 kb of GUF1, introns included, not only the 4.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GUF1 gene: GTP binding elongation factor GUF1. Retrieved 17 October 2026, from https://dantelabs.com/genes/guf1

Vancouver

Dante Labs. GUF1 gene: GTP binding elongation factor GUF1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/guf1

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