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Gene

DVL2

dishevelled segment polarity protein 2

Summary

Cytogenetic location
17p13.1
Coordinates
Chromosome 17: 7,225,342–7,234,517 (GRCh38)
Exons
15 exons across 9.2 kb
Protein
736 amino acids
MANE Select transcript
ENST00000005340.10NM_004422.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DVL2 yet. The test sequences your whole genome, so your data includes it all the same.

How DVL2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where DVL2 sits. DVL2 and 63 genes near it on chromosome 17, from 6,729,930 to 7,729,929.Chromosome 1717p13.1p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.36.8 Mb7 Mb7.2 Mb7.4 Mb7.6 MbXAF1: 6,755,375–6,775,647, forward strandXAF1FBXO39: 6,776,210–6,797,101, forward strandFBXO39TEKT1: 6,789,133–6,831,761, reverse strandTEKT1ALOX12: 6,996,049–7,010,754, forward strandRNASEK: 7,012,412–7,014,535, forward strandRNASEK-C17orf49: 7,012,635–7,017,520, forward strandBACC1: 7,014,480–7,017,544, forward strandBACC1BCL6B: 7,023,050–7,030,290, forward strandBCL6BSLC16A13: 7,035,981–7,041,031, forward strandSLC16A13SLC16A11: 7,041,605–7,044,092, reverse strandSLC16A11CLEC10A: 7,074,537–7,081,166, reverse strandCLEC10AASGR2: 7,100,166–7,116,603, reverse strandASGR2ASGR1: 7,172,427–7,179,666, reverse strandASGR1DLG4: 7,187,187–7,219,836, reverse strandACADVL: 7,217,125–7,225,273, forward strandACADVLDVL2: 7,225,342–7,234,517, reverse strandDVL2PHF23: 7,235,029–7,239,722, reverse strandPHF23GABARAP: 7,240,008–7,242,486, reverse strandGABARAP: 7,240,427–7,244,635, reverse strandCTDNEP1: 7,243,583–7,252,841, reverse strand: 7,246,829–7,262,089, reverse strandELP5: 7,250,818–7,260,165, forward strandCLDN7: 7,257,359–7,264,016, reverse strandSLC2A4: 7,281,664–7,289,241, forward strandYBX2: 7,288,253–7,294,750, reverse strandYBX2EIF5A: 7,306,944–7,312,506, forward strandEIF5AGPS2: 7,309,470–7,315,564, reverse strandGPS2: 7,312,661–7,319,174, reverse strandNEURL4: 7,315,628–7,329,393, reverse strandACAP1: 7,332,960–7,351,478, forward strandKCTD11: 7,351,889–7,354,944, forward strandTMEM95: 7,355,123–7,357,219, forward strandTNK1: 7,380,534–7,389,779, forward strandTNK1PLSCR3: 7,389,727–7,397,054, reverse strandPLSCR3TMEM256-PLSCR3: 7,389,734–7,404,097, reverse strandTMEM256: 7,402,774–7,404,138, reverse strandTMEM256NLGN2: 7,404,684–7,419,860, forward strandSPEM1: 7,420,323–7,421,637, forward strandSPEM2: 7,425,563–7,427,568, forward strandSPEM3: 7,428,857–7,432,820, forward strand: 7,428,861–7,436,278, forward strandTMEM102: 7,435,344–7,437,679, forward strandFGF11: 7,438,128–7,444,937, forward strandCHRNB1: 7,445,004–7,457,710, forward strandZBTB4: 7,459,366–7,484,278, reverse strandZBTB4SLC35G6: 7,481,446–7,483,496, forward strandSLC35G6POLR2A: 7,484,366–7,514,616, forward strandPOLR2ATNFSF12: 7,548,508–7,557,890, forward strandTNFSF12TNFSF12-TNFSF13: 7,549,099–7,561,601, forward strandTNFSF12-TNFSF13TNFSF13: 7,558,251–7,561,660, forward strandTNFSF13SENP3: 7,561,867–7,571,969, forward strandSENP3SENP3-EIF4A1: 7,563,287–7,578,715, forward strandEIF4A1: 7,572,718–7,579,007, forward strandCD68: 7,579,380–7,582,515, forward strandMPDU1: 7,583,214–7,594,419, forward strandSOX15: 7,588,178–7,590,101, reverse strandFXR2: 7,591,230–7,614,916, reverse strandSHBG: 7,613,946–7,633,469, forward strandSHBGSAT2: 7,626,234–7,627,879, reverse strandSAT2ATP1B2: 7,646,627–7,657,771, forward strandATP1B2TP53: 7,661,779–7,687,546, reverse strandTP53WRAP53: 7,686,071–7,703,505, forward strandWRAP53EFNB3: 7,705,172–7,711,372, forward strandEFNB3DNAH2: 7,717,728–7,833,742, forward strandDNAH2Diagram of DVL2: 15 exons on the reverse strand of chromosome 17Exon 15: 7,225,342–7,226,313, 972 basesExon 14: 7,226,421–7,226,639, 219 basesExon 13: 7,227,090–7,227,269, 180 basesExon 12: 7,227,404–7,227,535, 132 basesExon 11: 7,227,655–7,227,783, 129 basesExon 10: 7,227,977–7,228,044, 68 basesExon 9: 7,228,969–7,229,045, 77 basesExon 8: 7,229,135–7,229,274, 140 basesExon 7: 7,229,378–7,229,447, 70 basesExon 6: 7,229,588–7,229,678, 91 basesExon 5: 7,229,808–7,229,943, 136 basesExon 4: 7,230,046–7,230,155, 110 basesExon 3: 7,230,285–7,230,430, 146 basesExon 2: 7,230,728–7,230,797, 70 basesExon 1: 7,234,069–7,234,517, 449 bases1514131211109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3 kb of the gene's 9.2 kb; 2,211 of those bases code for the protein.

How a genome test reads DVL2

4

positions in DVL2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.2 kb of DVL2, introns included, not only the 3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DVL2 gene: dishevelled segment polarity protein 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/dvl2

Vancouver

Dante Labs. DVL2 gene: dishevelled segment polarity protein 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dvl2

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