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Gene

TNFSF12

TNF superfamily member 12

Summary

Cytogenetic location
17p13.1
Coordinates
Chromosome 17: 7,549,058–7,557,881 (GRCh38)
Exons
7 exons across 8.8 kb
Protein
249 amino acids
Also known as
TWEAK, DR3LG, APO3L, TNF12
MANE Select transcript
ENST00000293825.11NM_003809.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TNFSF12 yet. The test sequences your whole genome, so your data includes it all the same.

How TNFSF12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where TNFSF12 sits. TNFSF12 and 65 genes near it on chromosome 17, from 7,053,470 to 8,053,469.Chromosome 1717p13.1p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.37.2 Mb7.4 Mb7.6 Mb7.8 Mb8 MbCLEC10A: 7,074,537–7,081,166, reverse strandCLEC10AASGR2: 7,100,166–7,116,603, reverse strandASGR2ASGR1: 7,172,427–7,179,666, reverse strandASGR1DLG4: 7,187,187–7,219,836, reverse strandDLG4ACADVL: 7,217,125–7,225,273, forward strandDVL2: 7,225,338–7,234,538, reverse strandPHF23: 7,235,029–7,239,722, reverse strandGABARAP: 7,240,008–7,242,486, reverse strand: 7,240,427–7,244,635, reverse strandCTDNEP1: 7,243,583–7,252,841, reverse strand: 7,246,829–7,262,089, reverse strandELP5: 7,250,818–7,260,165, forward strandELP5CLDN7: 7,257,359–7,264,016, reverse strandCLDN7SLC2A4: 7,281,664–7,289,241, forward strandYBX2: 7,288,253–7,294,750, reverse strandYBX2EIF5A: 7,306,944–7,312,506, forward strandGPS2: 7,309,470–7,315,564, reverse strand: 7,312,661–7,319,174, reverse strandNEURL4: 7,315,628–7,329,393, reverse strandNEURL4ACAP1: 7,332,960–7,351,478, forward strandKCTD11: 7,351,889–7,354,944, forward strandKCTD11TMEM95: 7,355,123–7,357,219, forward strandTMEM95TNK1: 7,380,534–7,389,779, forward strandTNK1PLSCR3: 7,389,727–7,397,054, reverse strandPLSCR3TMEM256-PLSCR3: 7,389,734–7,404,097, reverse strandTMEM256: 7,402,774–7,404,138, reverse strandNLGN2: 7,404,684–7,419,860, forward strandSPEM1: 7,420,323–7,421,637, forward strandSPEM2: 7,425,563–7,427,568, forward strandSPEM3: 7,428,857–7,432,820, forward strand: 7,428,861–7,436,278, forward strandTMEM102: 7,435,344–7,437,679, forward strandFGF11: 7,438,128–7,444,937, forward strandFGF11CHRNB1: 7,445,004–7,457,710, forward strandCHRNB1ZBTB4: 7,459,366–7,484,278, reverse strandZBTB4SLC35G6: 7,481,446–7,483,496, forward strandSLC35G6POLR2A: 7,484,366–7,514,616, forward strandPOLR2ATNFSF12: 7,549,058–7,557,881, forward strandTNFSF12TNFSF12-TNFSF13: 7,549,099–7,561,601, forward strandTNFSF12-TNFSF13TNFSF13: 7,558,251–7,561,660, forward strandTNFSF13SENP3: 7,561,867–7,571,969, forward strandSENP3SENP3-EIF4A1: 7,563,287–7,578,715, forward strandEIF4A1: 7,572,718–7,579,007, forward strandCD68: 7,579,380–7,582,515, forward strandMPDU1: 7,583,214–7,594,419, forward strandSOX15: 7,588,178–7,590,101, reverse strandFXR2: 7,591,230–7,614,916, reverse strandSHBG: 7,613,946–7,633,469, forward strandSHBGSAT2: 7,626,234–7,627,879, reverse strandSAT2ATP1B2: 7,646,627–7,657,771, forward strandATP1B2TP53: 7,661,779–7,687,546, reverse strandTP53WRAP53: 7,686,071–7,703,505, forward strandWRAP53EFNB3: 7,705,172–7,711,372, forward strandEFNB3DNAH2: 7,717,728–7,833,742, forward strandDNAH2KDM6B: 7,834,193–7,854,808, forward strandKDM6BTMEM88: 7,855,057–7,856,114, forward strandTMEM88NAA38: 7,856,681–7,885,238, reverse strandNAA38CYB5D1: 7,857,696–7,862,282, forward strandCYB5D1CHD3: 7,884,787–7,912,760, forward strandCHD3RNF227: 7,913,238–7,916,377, reverse strandKCNAB3: 7,920,956–7,929,856, reverse strandKCNAB3: 7,925,931–7,930,622, reverse strandTRAPPC1: 7,930,345–7,932,123, reverse strandTRAPPC1CNTROB: 7,932,101–7,949,953, forward strandGUCY2D: 8,002,615–8,020,342, forward strandGUCY2DALOX15B: 8,039,011–8,049,134, forward strandALOX15BDiagram of TNFSF12: 7 exons on the forward strand of chromosome 17Exon 1: 7,549,058–7,549,312, 255 basesExon 2: 7,549,474–7,549,521, 48 basesExon 3: 7,550,120–7,550,195, 76 basesExon 4: 7,550,799–7,550,852, 54 basesExon 5: 7,550,943–7,550,978, 36 basesExon 6: 7,556,778–7,556,902, 125 basesExon 7: 7,557,099–7,557,881, 783 bases124675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.4 kb of the gene's 8.8 kb; 750 of those bases code for the protein.

Sequencing TNFSF12

7Low

How hard TNFSF12 is to sequence with short reads, out of 100

  • Mappability0%
  • Homology0%
  • Repeats11%
  • GC content53%
  • Reference coverage0%

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). TNFSF12 gene: TNF superfamily member 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/tnfsf12

Vancouver

Dante Labs. TNFSF12 gene: TNF superfamily member 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tnfsf12

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