Trait
Increased circulating interferon-gamma concentration
An elevation in the concentration of interferon gamma measured in the blood circulation.
Summary
- Also called
- Increased serum interferon-gamma level
- Body system
- Abnormality of the immune system
Reference genomeGRCh38hg38
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Get my Genome Test22 genes linked to Increased circulating interferon-gamma concentration
Changes in these genes cause rare conditions in which Increased circulating interferon-gamma concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| PSMB8proteasome 20S subunit beta 8 | Always | In 1 condition |
| PSMB9proteasome 20S subunit beta 9 | Always | In 1 condition |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Always | In 2 conditions |
| PRF1perforin 1 | Very often (80–99%) | In 1 condition |
| STX11syntaxin 11 | Very often (80–99%) | In 1 condition |
| STXBP2syntaxin binding protein 2 | Very often (80–99%) | In 1 condition |
| UNC13Dunc-13 homolog D | Very often (80–99%) | In 1 condition |
| ADARadenosine deaminase RNA specific | Often (30–79%) | In 1 condition |
| ANKRD55ankyrin repeat domain 55 | Often (30–79%) | In 1 condition |
| CD247CD247 molecule | Often (30–79%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Often (30–79%) | In 1 condition |
| IL2RAinterleukin 2 receptor subunit alpha | Often (30–79%) | In 1 condition |
| IL2RBinterleukin 2 receptor subunit beta | Often (30–79%) | In 1 condition |
| LSM11LSM11, U7 small nuclear RNA associated | Often (30–79%) | In 1 condition |
| PTPN2protein tyrosine phosphatase non-receptor type 2 | Often (30–79%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Often (30–79%) | In 1 condition |
| RNASEH2Aribonuclease H2 subunit A | Often (30–79%) | In 1 condition |
| RNASEH2Bribonuclease H2 subunit B | Often (30–79%) | In 1 condition |
| RNASEH2Cribonuclease H2 subunit C | Often (30–79%) | In 1 condition |
| RNU7-1RNA, U7 small nuclear 1 | Often (30–79%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| TREX1three prime repair exonuclease 1 | Often (30–79%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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