Trait
Immunologic hypersensitivity
Immunological states where the immune system produces harmful responses upon reexposure to sensitizing antigens.
Summary
- Body system
- Abnormality of the immune system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Immunologic hypersensitivity, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test19 genes linked to Immunologic hypersensitivity
Changes in these genes cause rare conditions in which Immunologic hypersensitivity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Very often (80–99%) | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Very often (80–99%) | In 1 condition |
| C4Acomplement C4A (Chido/Rodgers blood group) | Often (30–79%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Often (30–79%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Often (30–79%) | In 1 condition |
| FASFas cell surface death receptor | Often (30–79%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Often (30–79%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Often (30–79%) | In 1 condition |
| IL10interleukin 10 | Often (30–79%) | In 1 condition |
| IL12Ainterleukin 12A | Often (30–79%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Often (30–79%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Often (30–79%) | In 1 condition |
| KLRC4killer cell lectin like receptor C4 | Often (30–79%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Often (30–79%) | In 1 condition |
| STAT4signal transducer and activator of transcription 4 | Often (30–79%) | In 1 condition |
| TLR4toll like receptor 4 | Often (30–79%) | In 1 condition |
| UBAC2UBA domain containing 2 | Often (30–79%) | In 1 condition |
| CDH3cadherin 3 | Sometimes (5–29%) | In 1 condition |
| DNASE1L3deoxyribonuclease 1L3 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks