Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Excessive wrinkled skin, and the rest of your genome, with one test.
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Get my Genome Test31 genes linked to Excessive wrinkled skin
Changes in these genes cause rare conditions in which Excessive wrinkled skin is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Always | In 3 conditions |
| BUD13BUD13 spliceosome associated protein | Always | In 1 condition |
| COG7component of oligomeric golgi complex 7 | Always | In 2 conditions |
| PYCR1pyrroline-5-carboxylate reductase 1 | Always | In 2 conditions |
| ABCC6ATP binding cassette subfamily C member 6 | Very often (80–99%) | In 1 condition |
| ADAMTS2ADAM metallopeptidase with thrombospondin type 1 motif 2 | Very often (80–99%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Very often (80–99%) | In 1 condition |
| ATP6V1AATPase H+ transporting V1 subunit A | Very often (80–99%) | In 1 condition |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Very often (80–99%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Very often (80–99%) | In 2 conditions |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Very often (80–99%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Very often (80–99%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Very often (80–99%) | In 1 condition |
| MAP2K2mitogen-activated protein kinase kinase 2 | Very often (80–99%) | In 1 condition |
| PTENphosphatase and tensin homolog | Very often (80–99%) | In 1 condition |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Often (30–79%) | In 1 condition |
| COL3A1collagen type III alpha 1 chain | Often (30–79%) | In 1 condition |
| DKC1dyskerin pseudouridine synthase 1 | Often (30–79%) | In 1 condition |
| FGFR3fibroblast growth factor receptor 3 | Often (30–79%) | In 1 condition |
| PARNpoly(A)-specific ribonuclease | Often (30–79%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Often (30–79%) | In 1 condition |
| RTEL1regulator of telomere elongation helicase 1 | Often (30–79%) | In 1 condition |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Often (30–79%) | In 2 conditions |
| TERCtelomerase RNA component | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TINF2TERF1 interacting nuclear factor 2 | Often (30–79%) | In 1 condition |
| TWIST2twist family bHLH transcription factor 2 | Often (30–79%) | In 1 condition |
| H4C5H4 clustered histone 5 | Sometimes (5–29%) | In 1 condition |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Sometimes (5–29%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 1 condition |
| PLOD1procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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