{
  "url": "https://dantelabs.com/traits/diminished-ability-to-concentrate",
  "trait": {
    "bundleId": "2026.10.19-9814e911",
    "release": "2026-09-01",
    "slug": "diminished-ability-to-concentrate",
    "id": "HP:0031987",
    "name": "Poor concentration",
    "label": "Diminished ability to concentrate",
    "definition": "The inability to focus or concentrate on a specific task, activity, or object. The subject may find themselves unable to grasp or understand written text and re-reads frequently without understanding. Familiar tasks or activities are severely compromised due to the lack of ability to concentrate. Thinking through multi-step problems is typically very difficult or impossible, leading to avoidance of such activities.",
    "synonyms": [
      "Concentration problems",
      "Labored thinking",
      "Lack of concentration"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "disordered-formal-thought-process",
        "name": "Disordered formal thought process",
        "url": "https://dantelabs.com/traits/disordered-formal-thought-process"
      },
      {
        "slug": "reduced-attention-regulation",
        "name": "Reduced attention regulation",
        "url": "https://dantelabs.com/traits/reduced-attention-regulation"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ywhaz",
        "symbol": "YWHAZ",
        "hgnc": "HGNC:12855",
        "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ywhaz"
      },
      {
        "slug": "ada2",
        "symbol": "ADA2",
        "hgnc": "HGNC:1839",
        "name": "adenosine deaminase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ada2"
      },
      {
        "slug": "emc10",
        "symbol": "EMC10",
        "hgnc": "HGNC:27609",
        "name": "ER membrane protein complex subunit 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/emc10"
      },
      {
        "slug": "hnrnpc",
        "symbol": "HNRNPC",
        "hgnc": "HGNC:5035",
        "name": "heterogeneous nuclear ribonucleoprotein C",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnrnpc"
      },
      {
        "slug": "cmpk2",
        "symbol": "CMPK2",
        "hgnc": "HGNC:27015",
        "name": "cytidine/uridine monophosphate kinase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cmpk2"
      },
      {
        "slug": "dym",
        "symbol": "DYM",
        "hgnc": "HGNC:21317",
        "name": "dymeclin",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dym"
      },
      {
        "slug": "erf",
        "symbol": "ERF",
        "hgnc": "HGNC:3444",
        "name": "ETS2 repressor factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/erf"
      },
      {
        "slug": "hivep2",
        "symbol": "HIVEP2",
        "hgnc": "HGNC:4921",
        "name": "HIVEP zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hivep2"
      },
      {
        "slug": "jam2",
        "symbol": "JAM2",
        "hgnc": "HGNC:14686",
        "name": "junctional adhesion molecule 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/jam2"
      },
      {
        "slug": "myorg",
        "symbol": "MYORG",
        "hgnc": "HGNC:19918",
        "name": "myogenesis regulating glycosidase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myorg"
      },
      {
        "slug": "naa60",
        "symbol": "NAA60",
        "hgnc": "HGNC:25875",
        "name": "N-alpha-acetyltransferase 60, NatF catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/naa60"
      },
      {
        "slug": "pdgfb",
        "symbol": "PDGFB",
        "hgnc": "HGNC:8800",
        "name": "platelet derived growth factor subunit B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdgfb"
      },
      {
        "slug": "pdgfrb",
        "symbol": "PDGFRB",
        "hgnc": "HGNC:8804",
        "name": "platelet derived growth factor receptor beta",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdgfrb"
      },
      {
        "slug": "rrp12",
        "symbol": "RRP12",
        "hgnc": "HGNC:29100",
        "name": "ribosomal RNA processing 12 homolog",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rrp12"
      },
      {
        "slug": "slc20a2",
        "symbol": "SLC20A2",
        "hgnc": "HGNC:10947",
        "name": "solute carrier family 20 member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc20a2"
      },
      {
        "slug": "tmem163",
        "symbol": "TMEM163",
        "hgnc": "HGNC:25380",
        "name": "transmembrane protein 163",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem163"
      },
      {
        "slug": "xpr1",
        "symbol": "XPR1",
        "hgnc": "HGNC:12827",
        "name": "xenotropic and polytropic retrovirus receptor 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xpr1"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      },
      {
        "slug": "herc2",
        "symbol": "HERC2",
        "hgnc": "HGNC:4868",
        "name": "HECT and RLD domain containing E3 ubiquitin protein ligase 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/herc2"
      },
      {
        "slug": "polg",
        "symbol": "POLG",
        "hgnc": "HGNC:9179",
        "name": "DNA polymerase gamma, catalytic subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/polg"
      },
      {
        "slug": "tbl1x",
        "symbol": "TBL1X",
        "hgnc": "HGNC:11585",
        "name": "transducin beta like 1 X-linked",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbl1x"
      },
      {
        "slug": "trex1",
        "symbol": "TREX1",
        "hgnc": "HGNC:12269",
        "name": "three prime repair exonuclease 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trex1"
      },
      {
        "slug": "twnk",
        "symbol": "TWNK",
        "hgnc": "HGNC:1160",
        "name": "twinkle mtDNA helicase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/twnk"
      }
    ]
  }
}