Trait
Cataplexy
A sudden and transient episode of bilateral loss of muscle tone, often triggered by emotions.
Summary
- Body system
- Abnormality of the nervous system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Cataplexy, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test12 genes linked to Cataplexy
Changes in these genes cause rare conditions in which Cataplexy is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| DNMT1DNA methyltransferase 1 | Always | In 2 conditions |
| MOGmyelin oligodendrocyte glycoprotein | Always | In 2 conditions |
| CTSHcathepsin H | Very often (80–99%) | In 1 condition |
| HCRThypocretin neuropeptide precursor | Very often (80–99%) | In 2 conditions |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Very often (80–99%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Very often (80–99%) | In 1 condition |
| P2RY11purinergic receptor P2Y11 | Very often (80–99%) | In 1 condition |
| TNFSF4TNF superfamily member 4 | Very often (80–99%) | In 1 condition |
| ZNF365zinc finger protein 365 | Very often (80–99%) | In 1 condition |
| TBCDtubulin folding cofactor D | Sometimes (5–29%) | In 2 conditions |
| NPC1NPC intracellular cholesterol transporter 1 | Not recorded | In 1 condition |
| NPC2NPC intracellular cholesterol transporter 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks