Trait
Acral blistering
Bullae (defined as fluid-filled blisters more than 5 mm in diameter with thin walls) of the skin with an acral distribution (affecting peripheral regions such as hands and feet).
Summary
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test9 genes linked to Acral blistering
Changes in these genes cause rare conditions in which Acral blistering is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FBXO28F-box protein 28 | Always | In 1 condition |
| FERMT1FERM domain containing kindlin 1 | Always | In 1 condition |
| COL17A1collagen type XVII alpha 1 chain | Often (30–79%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Often (30–79%) | In 2 conditions |
| ITGB4integrin subunit beta 4 | Often (30–79%) | In 1 condition |
| KRT5keratin 5 | Often (30–79%) | In 1 condition |
| PLECplectin | Often (30–79%) | In 1 condition |
| SMARCAD1SNF2 related chromatin remodeling ATPase with DExD box 1 | Often (30–79%) | In 1 condition |
| KRT14keratin 14 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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