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Gene

ZBTB7A

zinc finger and BTB domain containing 7A

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 4,043,303–4,066,899 (GRCh38)
Exons
3 exons across 23.6 kb
Protein
584 amino acids
Also known as
FBI-1, LRF, DKFZp547O146, pokemon, ZNF857A
Previous symbols
ZBTB7
MANE Select transcript
ENST00000322357.9NM_015898.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ZBTB7A yet. The test sequences your whole genome, so your data includes it all the same.

How ZBTB7A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where ZBTB7A sits. ZBTB7A and 37 genes near it on chromosome 19, from 3,555,101 to 4,555,100.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.433.6 Mb3.8 Mb4 Mb4.2 Mb4.4 MbMFSD12: 3,538,261–3,574,290, reverse strandHMG20B: 3,572,692–3,579,088, forward strandHMG20BGIPC3: 3,585,474–3,593,541, forward strandGIPC3TBXA2R: 3,594,506–3,606,900, reverse strandTBXA2RCACTIN: 3,610,643–3,626,833, reverse strandCACTINPIP5K1C: 3,630,181–3,700,506, reverse strandPIP5K1CTJP3: 3,708,310–3,750,813, forward strandTJP3APBA3: 3,750,772–3,761,700, reverse strandAPBA3MRPL54: 3,761,841–3,769,033, forward strandMRPL54RAX2: 3,769,089–3,772,238, reverse strandRAX2MATK: 3,777,969–3,802,129, reverse strandMATKZFR2: 3,804,024–3,869,055, reverse strandZFR2ATCAY: 3,879,864–3,928,082, forward strandATCAYNMRK2: 3,932,994–3,943,081, forward strandNMRK2DAPK3: 3,958,453–3,971,130, reverse strandDAPK3EEF2: 3,976,044–3,985,479, reverse strandEEF2PIAS4: 4,007,690–4,039,386, forward strandPIAS4ZBTB7A: 4,043,303–4,066,899, reverse strandZBTB7AMAP2K2: 4,090,316–4,124,238, reverse strandMAP2K2CREB3L3: 4,152,949–4,173,057, forward strandCREB3L3SIRT6: 4,174,104–4,182,604, reverse strandSIRT6ANKRD24: 4,182,630–4,224,818, forward strandANKRD24EBI3: 4,229,267–4,238,167, forward strandEBI3YJU2: 4,247,062–4,269,091, forward strandYJU2SHD: 4,279,013–4,290,728, forward strandSHDTMIGD2: 4,292,227–4,302,431, reverse strandTMIGD2FSD1: 4,304,587–4,323,844, forward strandFSD1STAP2: 4,324,040–4,342,786, reverse strandSTAP2MPND: 4,343,527–4,360,086, forward strandMPNDSH3GL1: 4,360,367–4,400,573, reverse strandSH3GL1CHAF1A: 4,402,522–4,445,018, forward strandCHAF1AUBXN6: 4,444,999–4,457,794, reverse strandUBXN6HDGFL2: 4,472,244–4,502,225, forward strandHDGFL2PLIN4: 4,502,182–4,520,379, reverse strandPLIN4PLIN5: 4,522,527–4,535,285, reverse strandPLIN5: 4,528,427–4,540,067, reverse strandLRG1: 4,536,402–4,540,104, reverse strandLRG1SEMA6B: 4,542,588–4,581,795, reverse strandDiagram of ZBTB7A: 3 exons on the reverse strand of chromosome 19Exon 3: 3 known disease-causing sitesExon 2: 8 known disease-causing sitesExon 3: 4,043,303–4,048,244, 4,942 basesExon 2: 4,053,971–4,055,247, 1,277 basesExon 1: 4,066,682–4,066,899, 218 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.4 kb of the gene's 23.6 kb; 1,755 of those bases code for the protein.

How a genome test reads ZBTB7A

11

positions in ZBTB7A where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 23.6 kb of ZBTB7A, introns included, not only the 6.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ZBTB7A gene: zinc finger and BTB domain containing 7A. Retrieved 17 October 2026, from https://dantelabs.com/genes/zbtb7a

Vancouver

Dante Labs. ZBTB7A gene: zinc finger and BTB domain containing 7A [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/zbtb7a

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