Skip to content
Use your HSA or FSA funds

Gene

TRIP12

thyroid hormone receptor interactor 12

Summary

Cytogenetic location
2q36.3
Coordinates
Chromosome 2: 229,763,837–229,922,009 (GRCh38)
Exons
42 exons across 158.2 kb
Protein
2,067 amino acids
Also known as
KIAA0045, ULF, TRIPC
MANE Select transcript
ENST00000675903.1NM_001348323.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

    How TRIP12 is laid out

    • Coding sequence
    • Untranslated region
    • Intron
    • Direction of transcription
    • Known disease-causing sites
    • Stretches short reads find hard
    Chromosome 2, with a bracket where TRIP12 sits. TRIP12 and 6 genes near it on chromosome 2, from 229,342,923 to 230,342,922.Chromosome 22q36.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3229.4 Mb229.6 Mb229.8 Mb230 Mb230.2 MbDNER: 229,357,519–229,714,586, reverse strandDNERTRIP12: 229,763,837–229,922,009, reverse strandTRIP12FBXO36: 229,922,302–230,014,512, forward strandFBXO36SLC16A14: 230,034,974–230,069,004, reverse strandSLC16A14SP110: 230,165,186–230,225,729, reverse strandSP110SP140: 230,203,110–230,316,577, forward strandSP140SP140L: 230,326,762–230,407,086, forward strandSP140LDiagram of TRIP12: 42 exons on the reverse strand of chromosome 2Exon 42: 3 known disease-causing sitesExon 41: 1 known disease-causing siteExon 38: 2 known disease-causing sitesExon 37: 3 known disease-causing sitesExon 36: 1 known disease-causing siteExon 35: 1 known disease-causing siteExon 34: 2 known disease-causing sitesExon 33: 4 known disease-causing sitesExon 32: 2 known disease-causing sitesExon 31: 2 known disease-causing sitesExon 29: 2 known disease-causing sitesExon 27: 1 known disease-causing siteExon 26: 1 known disease-causing siteExon 25: 1 known disease-causing siteExon 24: 3 known disease-causing sitesExon 22: 1 known disease-causing siteExon 21: 2 known disease-causing sitesExon 19: 2 known disease-causing sitesExon 18: 3 known disease-causing sitesExon 15: 2 known disease-causing sitesExon 13: 2 known disease-causing sitesExon 11: 2 known disease-causing sitesExon 7: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 4: 4 known disease-causing sitesExon 42: 229,763,837–229,767,750, 3,914 basesExon 41: 229,768,616–229,768,719, 104 basesExon 40: 229,769,231–229,769,325, 95 basesExon 39: 229,771,519–229,771,632, 114 basesExon 38: 229,774,097–229,774,261, 165 basesExon 37: 229,777,315–229,777,479, 165 basesExon 36: 229,778,433–229,778,587, 155 basesExon 35: 229,778,876–229,778,990, 115 basesExon 34: 229,785,757–229,785,855, 99 basesExon 33: 229,787,505–229,787,661, 157 basesExon 32: 229,788,798–229,788,940, 143 basesExon 31: 229,789,611–229,789,762, 152 basesExon 30: 229,791,124–229,791,251, 128 basesExon 29: 229,791,866–229,792,065, 200 basesExon 28: 229,792,153–229,792,226, 74 basesExon 27: 229,792,973–229,793,145, 173 basesExon 26: 229,795,179–229,795,330, 152 basesExon 25: 229,796,591–229,796,782, 192 basesExon 24: 229,797,690–229,797,831, 142 basesExon 23: 229,798,875–229,799,049, 175 basesExon 22: 229,799,283–229,799,383, 101 basesExon 21: 229,802,252–229,802,459, 208 basesExon 20: 229,803,571–229,803,689, 119 basesExon 19: 229,803,999–229,804,227, 229 basesExon 18: 229,805,730–229,805,883, 154 basesExon 17: 229,807,708–229,807,864, 157 basesExon 16: 229,808,252–229,808,369, 118 basesExon 15: 229,810,880–229,811,045, 166 basesExon 14: 229,811,136–229,811,204, 69 basesExon 13: 229,813,870–229,814,031, 162 basesExon 12: 229,814,233–229,814,325, 93 basesExon 11: 229,815,099–229,815,194, 96 basesExon 10: 229,815,273–229,815,308, 36 basesExon 9: 229,818,364–229,818,512, 149 basesExon 8: 229,829,193–229,829,288, 96 basesExon 7: 229,830,756–229,830,839, 84 basesExon 6: 229,836,848–229,836,984, 137 basesExon 5: 229,840,822–229,840,927, 106 basesExon 4: 229,858,772–229,859,574, 803 basesExon 3: 229,860,406–229,860,531, 126 basesExon 2: 229,879,982–229,880,128, 147 basesExon 1: 229,921,880–229,922,009, 130 bases422515′3′

    Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

    Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

    Nearby genes from Ensembl release 116, on GRCh38.

    Exons make up 10.1 kb of the gene's 158.2 kb; 6,204 of those bases code for the protein.

    How a genome test reads TRIP12

    54

    positions in TRIP12 where ClinVar classes a change as pathogenic or likely pathogenic

    None of them falls in a region short reads find hard.

    A whole genome covers all 158.2 kb of TRIP12, introns included, not only the 10.1 kb of exons.

    Where this comes from

    • HGNC: the gene's symbol, name, other symbols and location.
    • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
    • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
    • The ACMG secondary findings list, SF v3.2.
    • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
    • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
    • Data release 2026.10.16-c6eea6bf.

    Cite this page

    APA

    Dante Labs. (n.d.). TRIP12 gene: thyroid hormone receptor interactor 12. Retrieved 16 October 2026, from https://dantelabs.com/genes/trip12

    Vancouver

    Dante Labs. TRIP12 gene: thyroid hormone receptor interactor 12 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/trip12

    One test. A lifetime of answers.

    From $449Free shipping · Results in 6–8 weeks

    Get my Genome Test