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Gene

SP140

SP140 nuclear body protein

Summary

Cytogenetic location
2q37.1
Coordinates
Chromosome 2: 230,225,736–230,313,215 (GRCh38)
Exons
27 exons across 87.5 kb
Protein
867 amino acids
Also known as
LYSP100-B, LYSP100-A
MANE Select transcript
ENST00000392045.8NM_007237.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SP140 yet. The test sequences your whole genome, so your data includes it all the same.

How SP140 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where SP140 sits. SP140 and 7 genes near it on chromosome 2, from 229,769,476 to 230,769,475.Chromosome 22q37.1p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.3229.8 Mb230 Mb230.2 Mb230.4 Mb230.6 MbTRIP12: 229,763,835–229,923,239, reverse strandTRIP12FBXO36: 229,922,302–230,014,512, forward strandFBXO36SLC16A14: 230,034,974–230,069,004, reverse strandSLC16A14SP110: 230,165,186–230,225,729, reverse strandSP110SP140: 230,225,736–230,313,215, forward strandSP140SP140L: 230,326,762–230,407,086, forward strandSP140LSP100: 230,414,871–230,545,700, forward strandSP100CAB39: 230,712,822–230,821,086, forward strandCAB39Diagram of SP140: 27 exons on the forward strand of chromosome 2Exon 1: 230,225,736–230,225,903, 168 basesExon 2: 230,237,083–230,237,260, 178 basesExon 3: 230,238,213–230,238,381, 169 basesExon 4: 230,241,404–230,241,487, 84 basesExon 5: 230,243,731–230,243,811, 81 basesExon 6: 230,244,988–230,245,080, 93 basesExon 7: 230,245,863–230,245,940, 78 basesExon 8: 230,247,916–230,248,065, 150 basesExon 9: 230,248,885–230,248,968, 84 basesExon 10: 230,250,981–230,251,061, 81 basesExon 11: 230,253,316–230,253,417, 102 basesExon 12: 230,255,452–230,255,532, 81 basesExon 13: 230,269,532–230,269,618, 87 basesExon 14: 230,269,837–230,269,953, 117 basesExon 15: 230,270,586–230,270,639, 54 basesExon 16: 230,284,346–230,284,411, 66 basesExon 17: 230,285,752–230,285,832, 81 basesExon 18: 230,287,892–230,287,966, 75 basesExon 19: 230,290,460–230,290,564, 105 basesExon 20: 230,292,646–230,292,788, 143 basesExon 21: 230,294,271–230,294,318, 48 basesExon 22: 230,297,421–230,297,462, 42 basesExon 23: 230,309,924–230,310,039, 116 basesExon 24: 230,310,743–230,310,851, 109 basesExon 25: 230,311,154–230,311,231, 78 basesExon 26: 230,311,452–230,311,595, 144 basesExon 27: 230,312,586–230,313,215, 630 bases11020275′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 87.5 kb; 2,604 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SP140 gene: SP140 nuclear body protein. Retrieved 17 October 2026, from https://dantelabs.com/genes/sp140

Vancouver

Dante Labs. SP140 gene: SP140 nuclear body protein [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sp140

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