Traits

Traits linked to TRDN

triadin

The Human Phenotype Ontology links 18 traits to TRDN, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the cardiovascular system

Trait	How often it is seen
Bidirectional ventricular tachycardia	Always
Extra heart beat	Always
Polymorphic ventricular tachycardia	Always
Effort-induced polymorphic ventricular tachycardia	Very often (80–99%)
Fainting spell	Very often (80–99%)
Atrial standstill	Often (30–79%)
Heart stops beating	Often (30–79%)
Paroxysmal atrial fibrillation	Often (30–79%)
Reduced systolic function	Often (30–79%)
Shock	Often (30–79%)
Stretched and thinned heart muscle	Often (30–79%)
Sudden cardiac death	Often (30–79%)
Interruption of electrical communication between upper and lower chambers of heart	Sometimes (5–29%)
Sick sinus syndrome	Sometimes (5–29%)
Ventricular couplet	Sometimes (5–29%)
Ventricular tachycardia	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Proximal neurogenic muscle weakness	Often (30–79%)

Abnormality of the nervous system

Trait	How often it is seen
Epilepsy	Not recorded

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to TRDN and how often each is seen. Find out more at hpo.jax.org.

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