Traits

Traits linked to SERPINF2

serpin family F member 2

The Human Phenotype Ontology links 12 traits to SERPINF2, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Bleeding within a joint	Very often (80–99%)
Excessive bleeding after minor trauma	Very often (80–99%)
Bleeding tendency	Often (30–79%)
Reduced euglobulin clot lysis time	Often (30–79%)
Abnormal umbilical stump bleeding	Sometimes (5–29%)
Bleeding gums	Sometimes (5–29%)
Bleeding within the skull	Sometimes (5–29%)
Bruising susceptibility	Sometimes (5–29%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Intramuscular hematoma	Often (30–79%)
Bone pain	Sometimes (5–29%)

Abnormality of the respiratory system

Trait	How often it is seen
Hemothorax	Often (30–79%)

Laboratory abnormality

Trait	How often it is seen
Blood in urine	Often (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to SERPINF2 and how often each is seen. Find out more at hpo.jax.org.

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