Trait

Peroneal muscle weakness

Weakness of the peroneal muscles.

HPO HP:0011727

Also called: Fibularis muscle weakness
Body system: Abnormality of limbs Abnormality of the musculoskeletal system

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8 genes linked to Peroneal muscle weakness

Changes in these genes cause rare conditions in which Peroneal muscle weakness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
LMNAlamin A/C	Always	In 1 condition
FKTNfukutin	Often (30–79%)	In 1 condition
GDAP1ganglioside induced differentiation associated protein 1	Often (30–79%)	In 1 condition
PMP22peripheral myelin protein 22	Often (30–79%)	In 1 condition
REEP1receptor accessory protein 1	Often (30–79%)	In 1 condition
GYG1glycogenin 1	Sometimes (5–29%)	In 1 condition
SARDHsarcosine dehydrogenase	Sometimes (5–29%)	In 1 condition
TRPV4transient receptor potential cation channel subfamily V member 4	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Distal lower limb muscle weakness

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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