Trait
Poorly mineralized tooth enamel
Clinical name: Enamel hypomineralization
A decreased amount of enamel mineralization. Hypomineralized enamel has a brown discoloration and brittle aspect.
Summary
- Also called
- Decreased enamel mineralisation, Hypomineralization of enamel, Mottled tooth enamel
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Poorly mineralized tooth enamel, and the rest of your genome, with one test.
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Get my Genome Test9 genes linked to Poorly mineralized tooth enamel
Changes in these genes cause rare conditions in which Poorly mineralized tooth enamel is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| AMTNamelotin | Always | In 1 condition |
| ENAMenamelin | Always | In 1 condition |
| KLK4kallikrein related peptidase 4 | Always | In 1 condition |
| DLX3distal-less homeobox 3 | Often (30–79%) | In 1 condition |
| DIAPH1diaphanous related formin 1 | Sometimes (5–29%) | In 1 condition |
| GPR68G protein-coupled receptor 68 | Not recorded | In 1 condition |
| ODAPHodontogenesis associated phosphoprotein | Not recorded | In 1 condition |
| PHEXphosphate regulating endopeptidase X-linked | Not recorded | In 1 condition |
| WDR72WD repeat domain 72 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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