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Gene

CYP3A5

cytochrome P450 family 3 subfamily A member 5

Summary

Cytogenetic location
7q22.1
Coordinates
Chromosome 7: 99,648,194–99,679,996 (GRCh38)
Exons
13 exons across 31.8 kb
Protein
502 amino acids
Also known as
PCN3, P450PCN3, CP35
MANE Select transcript
ENST00000222982.8NM_000777.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

CYP3A5 and medicines

How CYP3A5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where CYP3A5 sits. CYP3A5 and 39 genes near it on chromosome 7, from 99,164,095 to 100,164,094.Chromosome 77q22.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.399.2 Mb99.4 Mb99.6 Mb99.8 Mb100 MbKPNA7: 99,173,572–99,250,075, reverse strandKPNA7MYH16: 99,272,839–99,311,132, forward strandMYH16: 99,325,879–99,394,653, forward strandARPC1A: 99,325,879–99,366,527, forward strandARPC1AARPC1B: 99,374,226–99,398,124, forward strandARPC1BPDAP1: 99,392,048–99,408,831, reverse strandPDAP1BUD31: 99,408,610–99,419,618, forward strandPTCD1: 99,415,192–99,466,201, reverse strandATP5MF-PTCD1: 99,419,749–99,466,197, reverse strandCPSF4: 99,438,908–99,458,910, forward strandCPSF4ATP5MF: 99,448,475–99,466,201, reverse strandATP5MFZNF789: 99,472,794–99,503,650, forward strandZNF789ZNF394: 99,473,877–99,504,918, reverse strandZNF394ZKSCAN5: 99,504,634–99,535,360, forward strandZKSCAN5ZBED8L: 99,546,204–99,559,392, reverse strandZBED8LZNF655: 99,558,389–99,578,948, forward strandZNF655: 99,558,695–99,607,810, forward strandTMEM225B: 99,597,868–99,611,045, forward strandTMEM225BZSCAN25: 99,616,623–99,738,531, forward strandZSCAN25CYP3A5: 99,648,194–99,679,996, reverse strandCYP3A5CYP3A7-CYP3A51P: 99,684,957–99,735,102, reverse strandCYP3A7-CYP3A51PCYP3A7: 99,704,105–99,735,196, reverse strandCYP3A7CYP3A4: 99,756,954–99,784,327, reverse strandCYP3A4CYP3A43: 99,827,922–99,867,801, forward strandCYP3A43OR2AE1: 99,876,062–99,877,033, reverse strandOR2AE1TRIM4: 99,876,958–99,919,604, reverse strandTRIM4GJC3: 99,923,266–99,929,620, reverse strandGJC3AZGP1: 99,966,720–99,976,074, reverse strandAZGP1ZKSCAN1: 100,015,570–100,047,430, forward strandZKSCAN1ZSCAN21: 100,049,767–100,081,304, forward strandZSCAN21ZNF3: 100,056,868–100,082,706, reverse strandZNF3COPS6: 100,088,948–100,095,185, forward strandCOPS6MCM7: 100,092,233–100,101,940, reverse strandMCM7AP4M1: 100,100,841–100,110,345, forward strandTAF6: 100,106,876–100,127,187, reverse strandTAF6CNPY4: 100,119,614–100,125,511, forward strandMBLAC1: 100,126,694–100,128,498, forward strandLAMTOR4: 100,148,888–100,155,945, forward strandLAMTOR4TRAPPC14: 100,154,420–100,158,737, reverse strandGAL3ST4: 100,159,244–100,168,953, reverse strandGAL3ST4Diagram of CYP3A5: 13 exons on the reverse strand of chromosome 7Exon 13: 99,648,194–99,648,400, 207 basesExon 12: 99,650,073–99,650,232, 160 basesExon 11: 99,652,553–99,652,779, 227 basesExon 10: 99,660,499–99,660,659, 161 basesExon 9: 99,662,816–99,662,882, 67 basesExon 8: 99,663,968–99,664,095, 128 basesExon 7: 99,665,166–99,665,314, 149 basesExon 6: 99,666,601–99,666,689, 89 basesExon 5: 99,666,952–99,667,065, 114 basesExon 4: 99,672,580–99,672,679, 100 basesExon 3: 99,674,533–99,674,585, 53 basesExon 2: 99,676,115–99,676,208, 94 basesExon 1: 99,679,826–99,679,996, 171 bases131210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 31.8 kb; 1,509 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • CPIC and PharmGKB: the alleles, results and medicines.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). CYP3A5 gene: cytochrome P450 family 3 subfamily A member 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/cyp3a5

Vancouver

Dante Labs. CYP3A5 gene: cytochrome P450 family 3 subfamily A member 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cyp3a5

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