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Gene

INTS11

integrator complex subunit 11

Summary

Cytogenetic location
1p36.33
Coordinates
Chromosome 1: 1,311,600–1,324,660 (GRCh38)
Exons
17 exons across 13.1 kb
Protein
600 amino acids
Also known as
FLJ20542, RC-68, CPSF73L, INT11
Previous symbols
CPSF3L
MANE Select transcript
ENST00000435064.6NM_017871.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads INTS11 yet. The test sequences your whole genome, so your data includes it all the same.

How INTS11 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where INTS11 sits. INTS11 and 43 genes near it on chromosome 1, from 818,130 to 1,818,129.Chromosome 11p36.33p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q441 Mb1.2 Mb1.4 Mb1.6 Mb1.8 MbSAMD11: 923,895–944,590, forward strandNOC2L: 943,527–960,714, reverse strandKLHL17: 960,555–965,721, forward strandPLEKHN1: 966,437–975,865, forward strandPLEKHN1PERM1: 975,194–982,137, reverse strandPERM1HES4: 998,962–1,000,825, reverse strandHES4ISG15: 1,001,138–1,014,540, forward strandISG15AGRN: 1,020,069–1,056,119, forward strandAGRNRNF223: 1,070,967–1,074,306, reverse strandRNF223C1orf159: 1,081,811–1,116,361, reverse strandC1orf159TTLL10: 1,173,880–1,197,940, forward strandTNFRSF18: 1,203,508–1,206,814, reverse strandTNFRSF4: 1,211,326–1,214,153, reverse strandSDF4: 1,216,887–1,240,964, reverse strandSDF4B3GALT6: 1,232,237–1,235,041, forward strandB3GALT6C1QTNF12: 1,242,446–1,246,934, reverse strandC1QTNF12UBE2J2: 1,253,907–1,274,477, reverse strandUBE2J2SCNN1D: 1,280,436–1,292,029, forward strandACAP3: 1,292,376–1,309,609, reverse strandPUSL1: 1,308,547–1,311,679, forward strandPUSL1INTS11: 1,311,600–1,324,660, reverse strandINTS11CPTP: 1,324,756–1,328,897, forward strandCPTPTAS1R3: 1,331,275–1,335,314, forward strandTAS1R3DVL1: 1,335,275–1,349,962, reverse strandMXRA8: 1,352,683–1,361,800, reverse strandAURKAIP1: 1,373,710–1,375,521, reverse strandCCNL2: 1,385,709–1,400,909, reverse strandCCNL2MRPL20: 1,401,907–1,407,306, reverse strandMRPL20ANKRD65: 1,415,637–1,421,769, reverse strandANKRD65TMEM278: 1,425,871–1,430,255, forward strandTMEM278VWA1: 1,434,861–1,446,012, forward strandATAD3C: 1,449,689–1,470,163, forward strandATAD3B: 1,471,742–1,497,848, forward strandATAD3BATAD3A: 1,512,118–1,534,689, forward strandATAD3ATMEM240: 1,534,778–1,540,624, reverse strandTMEM240SSU72: 1,541,673–1,574,887, reverse strandSSU72FNDC10: 1,598,012–1,600,135, reverse strandFNDC10MIB2: 1,615,433–1,630,610, forward strandMIB2MMP23B: 1,631,660–1,635,263, forward strandMMP23BCDK11B: 1,635,225–1,659,267, reverse strandCDK11BSLC35E2B: 1,659,529–1,693,059, reverse strandSLC35E2BCDK11A: 1,702,379–1,724,571, reverse strandCDK11ANADK: 1,751,232–1,780,544, reverse strandNADKGNB1: 1,785,285–1,892,292, reverse strandGNB1Diagram of INTS11: 17 exons on the reverse strand of chromosome 1Exon 15: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 2: 1 known disease-causing siteExon 17: 1,311,600–1,311,924, 325 basesExon 16: 1,312,018–1,312,147, 130 basesExon 15: 1,312,226–1,312,368, 143 basesExon 14: 1,312,440–1,312,501, 62 basesExon 13: 1,312,593–1,312,700, 108 basesExon 12: 1,312,787–1,312,949, 163 basesExon 11: 1,313,035–1,313,124, 90 basesExon 10: 1,313,509–1,313,592, 84 basesExon 9: 1,313,732–1,313,921, 190 basesExon 8: 1,314,301–1,314,365, 65 basesExon 7: 1,314,824–1,314,962, 139 basesExon 6: 1,315,404–1,315,438, 35 basesExon 5: 1,315,520–1,315,618, 99 basesExon 4: 1,319,296–1,319,524, 229 basesExon 3: 1,320,456–1,320,529, 74 basesExon 2: 1,320,996–1,321,093, 98 basesExon 1: 1,324,581–1,324,660, 80 bases1716141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.1 kb of the gene's 13.1 kb; 1,803 of those bases code for the protein.

How a genome test reads INTS11

5

positions in INTS11 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 13.1 kb of INTS11, introns included, not only the 2.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). INTS11 gene: integrator complex subunit 11. Retrieved 16 October 2026, from https://dantelabs.com/genes/ints11

Vancouver

Dante Labs. INTS11 gene: integrator complex subunit 11 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ints11

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