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Gene

TNFRSF4

TNF receptor superfamily member 4

Summary

Cytogenetic location
1p36.33
Coordinates
Chromosome 1: 1,211,340–1,214,153 (GRCh38)
Exons
7 exons across 2.8 kb
Protein
277 amino acids
Also known as
ACT35, OX40, CD134
Previous symbols
TXGP1L
MANE Select transcript
ENST00000379236.4NM_003327.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TNFRSF4 yet. The test sequences your whole genome, so your data includes it all the same.

How TNFRSF4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 1, with a bracket where TNFRSF4 sits. TNFRSF4 and 41 genes near it on chromosome 1, from 712,747 to 1,712,746.Chromosome 11p36.33p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q440.8 Mb1 Mb1.2 Mb1.4 Mb1.6 MbSAMD11: 923,895–944,590, forward strandNOC2L: 943,527–960,714, reverse strandKLHL17: 960,555–965,721, forward strandPLEKHN1: 966,437–975,865, forward strandPLEKHN1PERM1: 975,194–982,137, reverse strandPERM1HES4: 998,962–1,000,825, reverse strandHES4ISG15: 1,001,138–1,014,540, forward strandISG15AGRN: 1,020,069–1,056,119, forward strandAGRNRNF223: 1,070,967–1,074,306, reverse strandRNF223C1orf159: 1,081,811–1,116,361, reverse strandC1orf159TTLL10: 1,173,880–1,197,940, forward strandTNFRSF18: 1,203,508–1,206,814, reverse strandTNFRSF18TNFRSF4: 1,211,340–1,214,153, reverse strandTNFRSF4SDF4: 1,216,887–1,240,964, reverse strandSDF4B3GALT6: 1,232,237–1,235,041, forward strandB3GALT6C1QTNF12: 1,242,446–1,246,934, reverse strandUBE2J2: 1,253,907–1,274,477, reverse strandSCNN1D: 1,280,436–1,292,029, forward strandSCNN1DACAP3: 1,292,376–1,309,609, reverse strandACAP3PUSL1: 1,308,547–1,311,679, forward strandPUSL1INTS11: 1,311,585–1,324,688, reverse strandINTS11CPTP: 1,324,756–1,328,897, forward strandTAS1R3: 1,331,275–1,335,314, forward strandDVL1: 1,335,275–1,349,962, reverse strandMXRA8: 1,352,683–1,361,800, reverse strandMXRA8AURKAIP1: 1,373,710–1,375,521, reverse strandCCNL2: 1,385,709–1,400,909, reverse strandCCNL2MRPL20: 1,401,907–1,407,306, reverse strandMRPL20ANKRD65: 1,415,637–1,421,769, reverse strandANKRD65TMEM278: 1,425,871–1,430,255, forward strandTMEM278VWA1: 1,434,861–1,446,012, forward strandATAD3C: 1,449,689–1,470,163, forward strandATAD3B: 1,471,742–1,497,848, forward strandATAD3BATAD3A: 1,512,118–1,534,689, forward strandATAD3ATMEM240: 1,534,778–1,540,624, reverse strandTMEM240SSU72: 1,541,673–1,574,887, reverse strandSSU72FNDC10: 1,598,012–1,600,135, reverse strandFNDC10MIB2: 1,615,433–1,630,610, forward strandMIB2MMP23B: 1,631,660–1,635,263, forward strandMMP23BCDK11B: 1,635,225–1,659,267, reverse strandCDK11BSLC35E2B: 1,659,529–1,693,059, reverse strandSLC35E2BCDK11A: 1,702,379–1,724,571, reverse strandCDK11ADiagram of TNFRSF4: 7 exons on the reverse strand of chromosome 1Exon 7: 1,211,340–1,211,625, 286 basesExon 6: 1,211,704–1,211,832, 129 basesExon 5: 1,211,942–1,212,138, 197 basesExon 4: 1,212,638–1,212,704, 67 basesExon 3: 1,212,992–1,213,093, 102 basesExon 2: 1,213,663–1,213,785, 123 basesExon 1: 1,213,983–1,214,153, 171 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.1 kb of the gene's 2.8 kb; 834 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). TNFRSF4 gene: TNF receptor superfamily member 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/tnfrsf4

Vancouver

Dante Labs. TNFRSF4 gene: TNF receptor superfamily member 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tnfrsf4

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