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Gene

GDF3

growth differentiation factor 3

Summary

Cytogenetic location
12p13.31
Coordinates
Chromosome 12: 7,689,784–7,695,775 (GRCh38)
Exons
2 exons across 6 kb
Protein
364 amino acids
MANE Select transcript
ENST00000329913.4NM_020634.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GDF3 yet. The test sequences your whole genome, so your data includes it all the same.

How GDF3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where GDF3 sits. GDF3 and 17 genes near it on chromosome 12, from 7,192,780 to 8,192,779.Chromosome 1212p13.31p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.337.2 Mb7.4 Mb7.6 Mb7.8 Mb8 MbPEX5: 7,188,653–7,218,574, forward strandPEX5ACSM4: 7,304,072–7,328,719, forward strandACSM4CD163L1: 7,346,685–7,479,897, reverse strandCD163L1CD163: 7,469,417–7,503,911, reverse strandCD163APOBEC1: 7,649,400–7,665,908, reverse strandAPOBEC1GDF3: 7,689,784–7,695,775, reverse strandGDF3DPPA3: 7,711,398–7,717,561, forward strandDPPA3CLEC4C: 7,724,646–7,751,620, reverse strandCLEC4CNANOGNB: 7,765,216–7,774,121, forward strandNANOGNBNANOG: 7,787,794–7,799,153, forward strandNANOGSLC2A14: 7,812,512–7,891,202, reverse strandSLC2A14SLC2A3: 7,919,228–8,019,007, reverse strandSLC2A3FOXJ2: 8,032,674–8,055,522, forward strandFOXJ2C3AR1: 8,056,844–8,066,440, reverse strandC3AR1NECAP1: 8,076,939–8,097,881, forward strandNECAP1CLEC4A: 8,123,617–8,138,607, forward strandCLEC4A: 8,138,140–8,175,320, forward strandZNF705A: 8,157,015–8,188,537, forward strandZNF705ADiagram of GDF3: 2 exons on the reverse strand of chromosome 12Exon 2: 1 known disease-causing siteExon 2: 7,689,784–7,690,704, 921 basesExon 1: 7,695,461–7,695,775, 315 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.2 kb of the gene's 6 kb; 1,095 of those bases code for the protein.

How a genome test reads GDF3

1

position in GDF3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6 kb of GDF3, introns included, not only the 1.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GDF3 gene: growth differentiation factor 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/gdf3

Vancouver

Dante Labs. GDF3 gene: growth differentiation factor 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/gdf3

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