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Gene

FAM111B

FAM111 trypsin like peptidase B

Summary

Cytogenetic location
11q12.1
Coordinates
Chromosome 11: 59,107,237–59,127,412 (GRCh38)
Exons
4 exons across 20.2 kb
Protein
734 amino acids
Also known as
CANP
MANE Select transcript
ENST00000343597.4NM_198947.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FAM111B yet. The test sequences your whole genome, so your data includes it all the same.

How FAM111B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where FAM111B sits. FAM111B and 18 genes near it on chromosome 11, from 58,617,325 to 59,617,324.Chromosome 1111q12.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2558.8 Mb59 Mb59.2 Mb59.4 Mb59.6 MbZFP91: 58,578,476–58,621,674, forward strandZFP91ZFP91-CNTF: 58,579,172–58,624,639, forward strandZFP91-CNTFCNTF: 58,622,660–58,626,826, forward strandCNTFGLYAT: 58,640,426–58,732,010, reverse strandGLYATGLYATL2: 58,834,065–58,904,215, reverse strandGLYATL2GLYATL1: 58,905,398–59,043,527, forward strandGLYATL1GLYATL1B: 59,086,307–59,094,786, forward strandGLYATL1BFAM111B: 59,107,237–59,127,412, forward strandFAM111BFAM111A: 59,142,703–59,155,042, forward strandFAM111ADTX4: 59,171,430–59,208,600, forward strandDTX4MPEG1: 59,208,510–59,213,474, reverse strandMPEG1OR5AN1: 59,358,895–59,371,714, forward strandOR5AN1OR5A2: 59,416,969–59,426,413, reverse strandOR5A2OR5A1: 59,436,469–59,451,380, forward strandOR5A1OR4D6: 59,456,961–59,457,905, forward strandOR4D6OR4D10: 59,473,315–59,479,361, forward strandOR4D10OR4D11: 59,503,576–59,504,511, forward strandOR4D11OR4D9: 59,511,368–59,520,703, forward strandOR4D9OSBP: 59,574,398–59,615,792, reverse strandOSBPDiagram of FAM111B: 4 exons on the forward strand of chromosome 11Exon 4: 1 known disease-causing siteExon 1: 59,107,237–59,107,296, 60 basesExon 2: 59,108,668–59,108,712, 45 basesExon 3: 59,109,540–59,109,706, 167 basesExon 4: 59,124,179–59,127,412, 3,234 bases12345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 20.2 kb; 2,205 of those bases code for the protein.

How a genome test reads FAM111B

1

position in FAM111B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 20.2 kb of FAM111B, introns included, not only the 3.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FAM111B gene: FAM111 trypsin like peptidase B. Retrieved 16 October 2026, from https://dantelabs.com/genes/fam111b

Vancouver

Dante Labs. FAM111B gene: FAM111 trypsin like peptidase B [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fam111b

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