Skip to content
Use your HSA or FSA funds

Trait

Subretinal fluid

Fluid accumulating between the neuroretina and retinal pigment epithelium.

HPO HP:0031526

Summary

Also called
Sub-retinal fluid
Body system
Abnormality of the eye

10 genes linked to Subretinal fluid

Changes in these genes cause rare conditions in which Subretinal fluid is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CTNNB1catenin beta 1Often (30–79%)In 1 condition
FZD4frizzled class receptor 4Often (30–79%)In 1 condition
LRP5LDL receptor related protein 5Often (30–79%)In 1 condition
NDPnorrin cystine knot growth factor NDPOften (30–79%)In 1 condition
TSPAN12tetraspanin 12Often (30–79%)In 1 condition
ZNF408zinc finger protein 408Often (30–79%)In 1 condition
CFHcomplement factor HSometimes (5–29%)In 1 condition
CFIcomplement factor ISometimes (5–29%)In 1 condition
EFEMP1EGF-like fibulin extracellular matrix protein 1Sometimes (5–29%)In 1 condition
BEST1bestrophin 1Not recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Retina issue

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test