Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Plethora, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test14 genes linked to Plethora
Changes in these genes cause rare conditions in which Plethora is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ARMC5armadillo repeat containing 5 | Often (30–79%) | In 1 condition |
| ATRXATRX chromatin remodeler | Often (30–79%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Often (30–79%) | In 1 condition |
| CDH23cadherin related 23 | Often (30–79%) | In 1 condition |
| GNASGNAS complex locus | Often (30–79%) | In 1 condition |
| KDM1Alysine demethylase 1A | Often (30–79%) | In 1 condition |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Often (30–79%) | In 1 condition |
| TP53tumor protein p53 | Often (30–79%) | In 1 condition |
| USP48ubiquitin specific peptidase 48 | Often (30–79%) | In 1 condition |
| USP8ubiquitin specific peptidase 8 | Often (30–79%) | In 1 condition |
| EPORerythropoietin receptor | Not recorded | In 1 condition |
| JAK2Janus kinase 2 | Not recorded | In 1 condition |
| SH2B3SH2B adaptor protein 3 | Not recorded | In 1 condition |
| VHLvon Hippel-Lindau tumor suppressor | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks