Trait

Hypoplastic helices

Underdevelopment of the helix, i.e., of the outer rim of the pinna.

Also called: Underdeveloped helices
Body system: Abnormality of the ear

This page as data

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library(jsonlite)

url <- "https://dantelabs.com/traits/hypoplastic-helices.json"
page <- fromJSON(url)
page$trait$name

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5 condition reports read genes linked to this trait

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Intellectual DisabilityReads 1 of these genesFOXP1About this report

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6 genes linked to Hypoplastic helices

Changes in these genes cause rare conditions in which Hypoplastic helices is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
HOXA2homeobox A2	Often (30–79%)	In 1 condition
AASSaminoadipate-semialdehyde synthase	Sometimes (5–29%)	In 1 condition
AGO2argonaute RISC catalytic component 2	Sometimes (5–29%)	In 1 condition
FOXP1forkhead box P1	Sometimes (5–29%)	In 1 condition
PAHphenylalanine hydroxylase	Rarely (1–4%)	In 1 condition
PBX1PBX homeobox 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Hypoplastic superior helix5 genes

Broader traits

Abnormal helix morphology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.18-8b139e39.

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