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Trait
Cutaneous melanoma
The presence of a melanoma of the skin.
Summary
Cutaneous melanomaHP:0012056
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Get my Genome Test23 genes linked to Cutaneous melanoma
Changes in these genes cause rare conditions in which Cutaneous melanoma is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| XPCXPC complex subunit, DNA damage recognition and repair factor | Often (30–79%) | In 1 condition |
| ALKALK receptor tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Sometimes (5–29%) | In 1 condition |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 2 conditions |
| COL7A1collagen type VII alpha 1 chain | Sometimes (5–29%) | In 4 conditions |
| FLCNfolliculin | Sometimes (5–29%) | In 1 condition |
| MC1Rmelanocortin 1 receptor | Sometimes (5–29%) | In 1 condition |
| MMP1matrix metallopeptidase 1 | Sometimes (5–29%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Sometimes (5–29%) | In 2 conditions |
| OCA2OCA2 melanosomal transmembrane protein | Sometimes (5–29%) | In 1 condition |
| PRDM10PR/SET domain 10 | Sometimes (5–29%) | In 1 condition |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Sometimes (5–29%) | In 1 condition |
| SOX5SRY-box transcription factor 5 | Sometimes (5–29%) | In 1 condition |
| WRNWRN RecQ like helicase | Sometimes (5–29%) | In 1 condition |
| ZEB2zinc finger E-box binding homeobox 2 | Sometimes (5–29%) | In 1 condition |
| CXCR4C-X-C motif chemokine receptor 4 | Rarely (1–4%) | In 1 condition |
| HRASHRas proto-oncogene, GTPase | Rarely (1–4%) | In 2 conditions |
| CDK4cyclin dependent kinase 4 | Not recorded | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Not recorded | In 2 conditions |
| COL17A1collagen type XVII alpha 1 chain | Not recorded | In 1 condition |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Not recorded | In 1 condition |
| MITFmelanocyte inducing transcription factor | Not recorded | In 1 condition |
| STK11serine/threonine kinase 11 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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