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Gene

TCHH

trichohyalin

Summary

Cytogenetic location
1q21.3
Coordinates
Chromosome 1: 152,106,317–152,115,444 (GRCh38)
Exons
3 exons across 9.1 kb
Protein
1,943 amino acids
Previous symbols
THH
MANE Select transcript
ENST00000614923.2NM_007113.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TCHH yet. The test sequences your whole genome, so your data includes it all the same.

How TCHH is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where TCHH sits. TCHH and 24 genes near it on chromosome 1, from 151,610,881 to 152,610,880.Chromosome 11q21.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44151.8 Mb152 Mb152.2 Mb152.4 Mb152.6 MbSNX27: 151,611,985–151,699,091, forward strandSNX27CELF3: 151,700,058–151,716,803, reverse strandCELF3RIIAD1: 151,710,433–151,729,805, forward strandRIIAD1MRPL9: 151,759,643–151,763,522, reverse strandMRPL9OAZ3: 151,762,899–151,771,334, forward strandOAZ3TDRKH: 151,769,799–151,791,416, reverse strandTDRKHLINGO4: 151,800,264–151,805,419, reverse strandLINGO4RORC: 151,806,021–151,831,845, reverse strandRORCC2CD4D: 151,837,818–151,840,557, reverse strandC2CD4DTHEM5: 151,847,101–151,853,712, reverse strandTHEM5THEM4: 151,870,866–151,909,879, reverse strandTHEM4S100A10: 151,981,697–151,993,891, reverse strandS100A10S100A11: 152,032,504–152,047,907, reverse strandS100A11TCHHL1: 152,084,141–152,089,064, reverse strandTCHHL1TCHH: 152,106,317–152,115,444, reverse strandTCHHRPTN: 152,153,595–152,159,228, reverse strandRPTNHRNR: 152,212,076–152,224,193, reverse strandHRNRFLG: 152,302,165–152,325,239, reverse strandFLGFLG2: 152,348,735–152,360,006, reverse strandFLG2CRNN: 152,409,242–152,414,279, reverse strandCRNNLCE5A: 152,510,803–152,512,177, forward strandLCE5ACRCT1: 152,514,482–152,516,008, forward strandCRCT1LCE3E: 152,565,654–152,566,780, reverse strandLCE3ELCE3D: 152,579,381–152,580,516, reverse strandLCE3DLCE3C: 152,600,234–152,601,086, forward strandLCE3CDiagram of TCHH: 3 exons on the reverse strand of chromosome 1Exon 3: 3 known disease-causing sitesExon 3: 152,106,317–152,113,078, 6,762 basesExon 2: 152,113,943–152,114,111, 169 basesExon 1: 152,115,391–152,115,444, 54 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7 kb of the gene's 9.1 kb; 5,832 of those bases code for the protein.

Sequencing TCHH

3

positions in TCHH where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 9.1 kb of TCHH, introns included, not only the 7 kb of exons.

Traits linked to TCHH

The Human Phenotype Ontology lists these as features of the rare conditions TCHH can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TCHH gene: trichohyalin. Retrieved 17 October 2026, from https://dantelabs.com/genes/tchh

Vancouver

Dante Labs. TCHH gene: trichohyalin [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tchh

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