Trait
Uncombable hair
Hair that is disorderly, stands out from the scalp, and cannot be combed flat.
Summary
- Body system
- Abnormality of the integument
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page$trait$nameRead the genes linked to Uncombable hair, and the rest of your genome, with one test.
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Get my Genome Test5 condition reports read genes linked to this trait
Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.
- Rare Monogenic Autoinflammatory DiseasesReads 2 of these genesSKIC2SKIC3About this report →
- Hereditary Hypotrichosis, Woolly Hair and MonilethrixReads 1 of these genesPADI3About this report →
- Ectodermal DysplasiasReads 1 of these genesTP63About this report →
- Female InfertilityReads 1 of these genesTP63About this report →
Show 1 more report
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Get my Genome Test7 genes linked to Uncombable hair
Changes in these genes cause rare conditions in which Uncombable hair is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| HRURFHR upstream open reading frame | Always | In 1 condition |
| TCHHtrichohyalin | Always | In 1 condition |
| TP63tumor protein p63 | Always | In 1 condition |
| SKIC2SKI2 subunit of superkiller complex | Often (30–79%) | In 2 conditions |
| SKIC3SKI3 subunit of superkiller complex | Often (30–79%) | In 1 condition |
| PADI3peptidyl arginine deiminase 3 | Not recorded | In 1 condition |
| TGM3transglutaminase 3 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.19-9814e911.
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