{
  "url": "https://dantelabs.com/genes/tchh",
  "gene": {
    "slug": "tchh",
    "symbol": "TCHH",
    "name": "trichohyalin",
    "hgnc": "HGNC:11791",
    "summary": null,
    "location": "1q21.3",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [
      "THH"
    ],
    "ensemblId": "ENSG00000159450",
    "entrezId": 7062,
    "omim": [
      "190370"
    ],
    "uniprot": [
      "Q07283"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "1",
      "start": 152106317,
      "end": 152115444,
      "strand": "-",
      "ensemblTranscript": "ENST00000614923.2",
      "refseqTranscript": "NM_007113.4",
      "ensemblProtein": "ENSP00000480484.1",
      "refseqProtein": "NP_009044.2",
      "exons": [
        {
          "start": 152106317,
          "end": 152113078
        },
        {
          "start": 152113943,
          "end": 152114111
        },
        {
          "start": 152115391,
          "end": 152115444
        }
      ],
      "cds": {
        "start": 152107385,
        "end": 152114080
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "1",
      "start": 152078793,
      "end": 152086556,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 151610881,
      "end": 152610880,
      "genes": [
        {
          "symbol": "SNX27",
          "ensemblId": "ENSG00000143376",
          "biotype": "protein_coding",
          "start": 151611985,
          "end": 151699091,
          "strand": "+",
          "slug": "snx27"
        },
        {
          "symbol": "CELF3",
          "ensemblId": "ENSG00000159409",
          "biotype": "protein_coding",
          "start": 151700058,
          "end": 151716803,
          "strand": "-",
          "slug": "celf3"
        },
        {
          "symbol": "RIIAD1",
          "ensemblId": "ENSG00000178796",
          "biotype": "protein_coding",
          "start": 151710433,
          "end": 151729805,
          "strand": "+",
          "slug": "riiad1"
        },
        {
          "symbol": "MRPL9",
          "ensemblId": "ENSG00000143436",
          "biotype": "protein_coding",
          "start": 151759643,
          "end": 151763522,
          "strand": "-",
          "slug": "mrpl9"
        },
        {
          "symbol": "OAZ3",
          "ensemblId": "ENSG00000143450",
          "biotype": "protein_coding",
          "start": 151762899,
          "end": 151771334,
          "strand": "+",
          "slug": "oaz3"
        },
        {
          "symbol": "TDRKH",
          "ensemblId": "ENSG00000182134",
          "biotype": "protein_coding",
          "start": 151769799,
          "end": 151791416,
          "strand": "-",
          "slug": "tdrkh"
        },
        {
          "symbol": "LINGO4",
          "ensemblId": "ENSG00000213171",
          "biotype": "protein_coding",
          "start": 151800264,
          "end": 151805419,
          "strand": "-",
          "slug": "lingo4"
        },
        {
          "symbol": "RORC",
          "ensemblId": "ENSG00000143365",
          "biotype": "protein_coding",
          "start": 151806021,
          "end": 151831845,
          "strand": "-",
          "slug": "rorc"
        },
        {
          "symbol": "C2CD4D",
          "ensemblId": "ENSG00000225556",
          "biotype": "protein_coding",
          "start": 151837818,
          "end": 151840557,
          "strand": "-",
          "slug": "c2cd4d"
        },
        {
          "symbol": "THEM5",
          "ensemblId": "ENSG00000196407",
          "biotype": "protein_coding",
          "start": 151847101,
          "end": 151853712,
          "strand": "-",
          "slug": "them5"
        },
        {
          "symbol": "THEM4",
          "ensemblId": "ENSG00000159445",
          "biotype": "protein_coding",
          "start": 151870866,
          "end": 151909879,
          "strand": "-",
          "slug": "them4"
        },
        {
          "symbol": "S100A10",
          "ensemblId": "ENSG00000197747",
          "biotype": "protein_coding",
          "start": 151981697,
          "end": 151993891,
          "strand": "-",
          "slug": "s100a10"
        },
        {
          "symbol": "S100A11",
          "ensemblId": "ENSG00000163191",
          "biotype": "protein_coding",
          "start": 152032504,
          "end": 152047907,
          "strand": "-",
          "slug": "s100a11"
        },
        {
          "symbol": "TCHHL1",
          "ensemblId": "ENSG00000182898",
          "biotype": "protein_coding",
          "start": 152084141,
          "end": 152089064,
          "strand": "-",
          "slug": "tchhl1"
        },
        {
          "symbol": "RPTN",
          "ensemblId": "ENSG00000215853",
          "biotype": "protein_coding",
          "start": 152153595,
          "end": 152159228,
          "strand": "-",
          "slug": "rptn"
        },
        {
          "symbol": "HRNR",
          "ensemblId": "ENSG00000197915",
          "biotype": "protein_coding",
          "start": 152212076,
          "end": 152224193,
          "strand": "-",
          "slug": "hrnr"
        },
        {
          "symbol": "FLG",
          "ensemblId": "ENSG00000143631",
          "biotype": "protein_coding",
          "start": 152302165,
          "end": 152325239,
          "strand": "-",
          "slug": "flg"
        },
        {
          "symbol": "FLG2",
          "ensemblId": "ENSG00000143520",
          "biotype": "protein_coding",
          "start": 152348735,
          "end": 152360006,
          "strand": "-",
          "slug": "flg2"
        },
        {
          "symbol": "CRNN",
          "ensemblId": "ENSG00000143536",
          "biotype": "protein_coding",
          "start": 152409242,
          "end": 152414279,
          "strand": "-",
          "slug": "crnn"
        },
        {
          "symbol": "LCE5A",
          "ensemblId": "ENSG00000186207",
          "biotype": "protein_coding",
          "start": 152510803,
          "end": 152512177,
          "strand": "+",
          "slug": "lce5a"
        },
        {
          "symbol": "CRCT1",
          "ensemblId": "ENSG00000169509",
          "biotype": "protein_coding",
          "start": 152514482,
          "end": 152516008,
          "strand": "+",
          "slug": "crct1"
        },
        {
          "symbol": "LCE3E",
          "ensemblId": "ENSG00000185966",
          "biotype": "protein_coding",
          "start": 152565654,
          "end": 152566780,
          "strand": "-",
          "slug": "lce3e"
        },
        {
          "symbol": "LCE3D",
          "ensemblId": "ENSG00000163202",
          "biotype": "protein_coding",
          "start": 152579381,
          "end": 152580516,
          "strand": "-",
          "slug": "lce3d"
        },
        {
          "symbol": "LCE3C",
          "ensemblId": "ENSG00000244057",
          "biotype": "protein_coding",
          "start": 152600234,
          "end": 152601086,
          "strand": "+",
          "slug": "lce3c"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "brittle-hair",
        "name": "Brittle hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/brittle-hair"
      },
      {
        "slug": "curly-hair",
        "name": "Curly hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/curly-hair"
      },
      {
        "slug": "pili-canaliculi",
        "name": "Pili canaliculi",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/pili-canaliculi"
      },
      {
        "slug": "uncombable-hair",
        "name": "Uncombable hair",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/uncombable-hair"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}