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Gene

SHROOM2

shroom family member 2

Summary

Cytogenetic location
Xp22.2
Coordinates
Chromosome X: 9,786,429–9,949,443 (GRCh38)
Exons
10 exons across 163 kb
Protein
1,616 amino acids
Previous symbols
APXL
MANE Select transcript
ENST00000380913.8NM_001649.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SHROOM2 yet. The test sequences your whole genome, so your data includes it all the same.

How SHROOM2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where SHROOM2 sits. SHROOM2 and 6 genes near it on chromosome X, from 9,367,936 to 10,367,935.Chromosome XXp22.2p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q289.4 Mb9.6 Mb9.8 Mb10 Mb10.2 MbTBL1X: 9,463,258–9,741,723, forward strandTBL1XGPR143: 9,724,039–9,786,297, reverse strandGPR143SHROOM2: 9,786,429–9,949,443, forward strandSHROOM2: 9,786,429–9,968,352, forward strandCLDN34: 9,961,424–9,968,352, forward strandCLDN34WWC3: 10,015,254–10,144,592, forward strandWWC3CLCN4: 10,156,938–10,237,663, forward strandCLCN4Diagram of SHROOM2: 10 exons on the forward strand of chromosome XExon 4: 1 known disease-causing siteExon 1: 9,786,429–9,786,710, 282 basesExon 2: 9,873,652–9,873,803, 152 basesExon 3: 9,890,977–9,891,108, 132 basesExon 4: 9,894,358–9,896,698, 2,341 basesExon 5: 9,898,190–9,898,290, 101 basesExon 6: 9,932,175–9,932,870, 696 basesExon 7: 9,937,134–9,937,685, 552 basesExon 8: 9,939,195–9,939,366, 172 basesExon 9: 9,944,641–9,944,913, 273 basesExon 10: 9,946,671–9,949,443, 2,773 bases12468105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.5 kb of the gene's 163 kb; 4,851 of those bases code for the protein.

How a genome test reads SHROOM2

1

position in SHROOM2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 163 kb of SHROOM2, introns included, not only the 7.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SHROOM2 gene: shroom family member 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/shroom2

Vancouver

Dante Labs. SHROOM2 gene: shroom family member 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/shroom2

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