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Gene

MYO18B

myosin XVIIIB

Summary

Cytogenetic location
22q12.1
Coordinates
Chromosome 22: 25,742,188–26,031,045 (GRCh38)
Exons
44 exons across 288.9 kb
Protein
2,567 amino acids
Also known as
BK125H2.1
MANE Select transcript
ENST00000335473.12NM_032608.7
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MYO18B yet. The test sequences your whole genome, so your data includes it all the same.

How MYO18B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 22, with a bracket where MYO18B sits. MYO18B and 2 genes near it on chromosome 22, from 25,386,617 to 26,386,616.Chromosome 2222q12.1p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3325.4 Mb25.6 Mb25.8 Mb26 Mb26.2 MbGRK3: 25,564,432–25,729,294, forward strandGRK3MYO18B: 25,742,188–26,031,045, forward strandMYO18BSEZ6L: 26,169,120–26,383,597, forward strandSEZ6LDiagram of MYO18B: 44 exons on the forward strand of chromosome 22Exon 2: 1 known disease-causing siteExon 3: 1 known disease-causing siteExon 4: 6 known disease-causing sitesExon 13: 1 known disease-causing siteExon 15: 1 known disease-causing siteExon 17: 2 known disease-causing sitesExon 19: 1 known disease-causing siteExon 21: 1 known disease-causing siteExon 23: 1 known disease-causing siteExon 24: 1 known disease-causing siteExon 28: 1 known disease-causing siteExon 29: 2 known disease-causing sitesExon 31: 3 known disease-causing sitesExon 38: 1 known disease-causing siteExon 42: 1 known disease-causing siteExon 43: 8 known disease-causing sitesExon 1: 25,742,188–25,742,293, 106 basesExon 2: 25,760,984–25,761,131, 148 basesExon 3: 25,763,231–25,763,389, 159 basesExon 4: 25,768,115–25,769,428, 1,314 basesExon 5: 25,770,110–25,770,176, 67 basesExon 6: 25,770,872–25,770,984, 113 basesExon 7: 25,772,334–25,772,510, 177 basesExon 8: 25,777,583–25,777,781, 199 basesExon 9: 25,780,056–25,780,198, 143 basesExon 10: 25,781,734–25,781,834, 101 basesExon 11: 25,785,428–25,785,491, 64 basesExon 12: 25,797,953–25,798,097, 145 basesExon 13: 25,823,505–25,823,678, 174 basesExon 14: 25,826,409–25,826,499, 91 basesExon 15: 25,828,776–25,828,968, 193 basesExon 16: 25,832,917–25,832,997, 81 basesExon 17: 25,835,296–25,835,443, 148 basesExon 18: 25,843,735–25,843,894, 160 basesExon 19: 25,846,100–25,846,283, 184 basesExon 20: 25,847,430–25,847,652, 223 basesExon 21: 25,851,470–25,851,579, 110 basesExon 22: 25,868,320–25,868,385, 66 basesExon 23: 25,874,286–25,874,414, 129 basesExon 24: 25,876,189–25,876,332, 144 basesExon 25: 25,877,959–25,878,048, 90 basesExon 26: 25,890,756–25,890,875, 120 basesExon 27: 25,891,304–25,891,412, 109 basesExon 28: 25,895,156–25,895,280, 125 basesExon 29: 25,898,307–25,898,461, 155 basesExon 30: 25,902,613–25,902,736, 124 basesExon 31: 25,903,631–25,903,831, 201 basesExon 32: 25,908,322–25,908,432, 111 basesExon 33: 25,910,946–25,911,050, 105 basesExon 34: 25,921,257–25,921,409, 153 basesExon 35: 25,946,137–25,946,250, 114 basesExon 36: 25,947,712–25,947,828, 117 basesExon 37: 25,950,367–25,950,450, 84 basesExon 38: 25,952,286–25,952,423, 138 basesExon 39: 25,955,179–25,955,364, 186 basesExon 40: 25,992,363–25,992,493, 131 basesExon 41: 26,003,265–26,003,309, 45 basesExon 42: 26,004,718–26,004,855, 138 basesExon 43: 26,026,445–26,027,690, 1,246 basesExon 44: 26,030,443–26,031,045, 603 bases1510152025303540445′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8.5 kb of the gene's 288.9 kb; 7,704 of those bases code for the protein.

How a genome test reads MYO18B

36

positions in MYO18B where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 288.9 kb of MYO18B, introns included, not only the 8.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MYO18B gene: myosin XVIIIB. Retrieved 16 October 2026, from https://dantelabs.com/genes/myo18b

Vancouver

Dante Labs. MYO18B gene: myosin XVIIIB [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/myo18b

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