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Gene

KIRREL1

kirre like nephrin family adhesion molecule 1

Summary

Cytogenetic location
1q23.1
Coordinates
Chromosome 1: 157,993,645–158,100,262 (GRCh38)
Exons
15 exons across 106.6 kb
Protein
757 amino acids
Also known as
NEPH1
Previous symbols
KIRREL
MANE Select transcript
ENST00000359209.11NM_018240.7
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KIRREL1 yet. The test sequences your whole genome, so your data includes it all the same.

How KIRREL1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 1, with a bracket where KIRREL1 sits. KIRREL1 and 17 genes near it on chromosome 1, from 157,546,954 to 158,546,953.Chromosome 11q23.1p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44157.6 Mb157.8 Mb158 Mb158.2 Mb158.4 MbFCRL5: 157,513,377–157,552,515, reverse strandFCRL5FCRL4: 157,573,747–157,598,085, reverse strandFCRL4FCRL3: 157,674,321–157,700,901, reverse strandFCRL3FCRL2: 157,745,733–157,777,269, reverse strandFCRL2FCRL1: 157,792,249–157,820,183, reverse strandFCRL1CD5L: 157,827,034–157,898,256, reverse strandCD5LKIRREL1: 157,993,645–158,100,262, forward strandKIRREL1SMIM42: 158,127,287–158,128,301, reverse strandSMIM42CD1D: 158,178,012–158,186,427, forward strandCD1DCD1A: 158,254,415–158,258,269, forward strandCD1ACD1C: 158,289,769–158,294,774, forward strandCD1CCD1B: 158,327,951–158,331,538, reverse strandCD1BCD1E: 158,353,696–158,357,553, forward strandCD1EOR10T2: 158,398,522–158,399,466, reverse strandOR10T2OR10K2: 158,418,210–158,426,237, reverse strandOR10K2OR10K1: 158,461,574–158,470,857, forward strandOR10K1OR10R2: 158,472,220–158,480,936, forward strandOR10R2OR6Y1: 158,544,550–158,554,405, reverse strandOR6Y1Diagram of KIRREL1: 15 exons on the forward strand of chromosome 1Exon 13: 1 known disease-causing siteExon 1: 157,993,645–157,993,728, 84 basesExon 2: 158,076,113–158,076,262, 150 basesExon 3: 158,077,991–158,078,140, 150 basesExon 4: 158,084,422–158,084,579, 158 basesExon 5: 158,086,596–158,086,746, 151 basesExon 6: 158,087,755–158,087,860, 106 basesExon 7: 158,088,006–158,088,154, 149 basesExon 8: 158,088,327–158,088,454, 128 basesExon 9: 158,089,502–158,089,628, 127 basesExon 10: 158,089,718–158,089,818, 101 basesExon 11: 158,091,358–158,091,556, 199 basesExon 12: 158,093,339–158,093,446, 108 basesExon 13: 158,093,623–158,093,762, 140 basesExon 14: 158,094,313–158,094,390, 78 basesExon 15: 158,094,644–158,100,262, 5,619 bases1510155′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.4 kb of the gene's 106.6 kb; 2,274 of those bases code for the protein.

How a genome test reads KIRREL1

1

position in KIRREL1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 106.6 kb of KIRREL1, introns included, not only the 7.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KIRREL1 gene: kirre like nephrin family adhesion molecule 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/kirrel1

Vancouver

Dante Labs. KIRREL1 gene: kirre like nephrin family adhesion molecule 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kirrel1

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