Trait
Mesangial hypercellularity
Increased numbers of mesangial cells per glomerulus, defined as more than 3 nuclei fully surrounded by matrix in one or more mesangial areas, not including perihilar region, on a standard 3-micron-thick tissue section, best evaluated on periodic acid-Schiff (PAS) stain.
Summary
- Also called
- Mesangial proliferation
- Body system
- Abnormality of the genitourinary system
Reference genomeGRCh38hg38
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Get my Genome Test9 genes linked to Mesangial hypercellularity
Changes in these genes cause rare conditions in which Mesangial hypercellularity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CFHR5complement factor H related 5 | Very often (80–99%) | In 1 condition |
| DGKEdiacylglycerol kinase epsilon | Very often (80–99%) | In 1 condition |
| LAMB2laminin subunit beta 2 | Very often (80–99%) | In 1 condition |
| KIRREL1kirre like nephrin family adhesion molecule 1 | Often (30–79%) | In 1 condition |
| NOP10NOP10 ribonucleoprotein | Often (30–79%) | In 1 condition |
| SGPL1sphingosine-1-phosphate lyase 1 | Often (30–79%) | In 1 condition |
| COPAcoat protein complex I subunit alpha | Sometimes (5–29%) | In 1 condition |
| APOEapolipoprotein E | Not recorded | In 1 condition |
| SPRY2sprouty RTK signaling antagonist 2 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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