Gene
KCNE3
potassium voltage-gated channel subfamily E regulatory subunit 3
- HGNC 6243↗(opens in a new tab)
- Ensembl gene ENSG00000175538↗(opens in a new tab)
- NCBI Gene 10008↗(opens in a new tab)
Summary
- Cytogenetic location
- 11q13.4
- Coordinates
- Chromosome 11: 74,454,841–74,467,549 (GRCh38)
- Exons
- 3 exons across 12.7 kb
- Protein
- 103 amino acids
- Also known as
- MiRP2, HOKPP
- MANE Select transcript
- ENST00000310128.9NM_005472.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How KCNE3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.1 kb of the gene's 12.7 kb; 312 of those bases code for the protein.
Traits linked to KCNE3
The Human Phenotype Ontology lists these as features of the rare conditions KCNE3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the musculoskeletal system
- Abnormal muscle fiber morphology
- EMG abnormality
- Episodic flaccid weakness
- Exercise-induced muscle fatigue
- Decreased lung function due to weak breathing muscles
- Fatty replacement of skeletal muscle
- Late-onset proximal muscle weakness
- Muscle spasm
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). KCNE3 gene: potassium voltage-gated channel subfamily E regulatory subunit 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/kcne3
Dante Labs. KCNE3 gene: potassium voltage-gated channel subfamily E regulatory subunit 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kcne3
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