Skip to content
Use your HSA or FSA funds

Gene

HS6ST2

heparan sulfate 6-O-sulfotransferase 2

Summary

Cytogenetic location
Xq26.2
Coordinates
Chromosome X: 132,626,015–132,958,629 (GRCh38)
Exons
5 exons across 332.6 kb
Protein
645 amino acids
Also known as
HS6ST-2
MANE Select transcript
ENST00000370833.7NM_001394073.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads HS6ST2 yet. The test sequences your whole genome, so your data includes it all the same.

How HS6ST2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where HS6ST2 sits. HS6ST2 and 3 genes near it on chromosome X, from 132,292,322 to 133,292,321.Chromosome XXq26.2p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q28132.4 Mb132.6 Mb132.8 Mb133 Mb133.2 MbMBNL3: 132,369,320–132,490,155, reverse strandMBNL3HS6ST2: 132,626,015–132,958,629, reverse strandHS6ST2USP26: 133,023,168–133,097,109, reverse strandUSP26TFDP3: 133,216,662–133,218,354, reverse strandTFDP3Diagram of HS6ST2: 5 exons on the reverse strand of chromosome XExon 2: 1 known disease-causing siteExon 5: 132,626,015–132,629,093, 3,079 basesExon 4: 132,669,113–132,669,199, 87 basesExon 3: 132,708,462–132,708,494, 33 basesExon 2: 132,956,808–132,957,326, 519 basesExon 1: 132,958,175–132,958,629, 455 bases515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.2 kb of the gene's 332.6 kb; 1,938 of those bases code for the protein.

How a genome test reads HS6ST2

1

position in HS6ST2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 332.6 kb of HS6ST2, introns included, not only the 4.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). HS6ST2 gene: heparan sulfate 6-O-sulfotransferase 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/hs6st2

Vancouver

Dante Labs. HS6ST2 gene: heparan sulfate 6-O-sulfotransferase 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hs6st2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test