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Gene

ESRP1

epithelial splicing regulatory protein 1

Summary

Cytogenetic location
8q22.1
Coordinates
Chromosome 8: 94,641,174–94,707,466 (GRCh38)
Exons
16 exons across 66.3 kb
Protein
681 amino acids
Also known as
FLJ20171
Previous symbols
RBM35A
MANE Select transcript
ENST00000433389.8NM_017697.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads ESRP1 yet. The test sequences your whole genome, so your data includes it all the same.

How ESRP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 8, with a bracket where ESRP1 sits. ESRP1 and 11 genes near it on chromosome 8, from 94,174,320 to 95,174,319.Chromosome 88q22.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.394.2 Mb94.4 Mb94.6 Mb94.8 Mb95 MbCDH17: 94,124,381–94,217,303, reverse strandCDH17GEM: 94,249,249–94,262,461, reverse strandGEMRAD54B: 94,371,960–94,475,134, reverse strandRAD54BFSBP: 94,378,377–94,436,952, reverse strandFSBPVIRMA: 94,487,689–94,553,529, reverse strandVIRMAESRP1: 94,641,174–94,707,466, forward strandESRP1DPY19L4: 94,719,677–94,793,836, forward strandDPY19L4INTS8: 94,813,311–94,881,746, forward strandINTS8CCNE2: 94,874,347–94,896,680, reverse strandCCNE2NDUFAF6: 94,895,533–95,116,455, forward strandNDUFAF6TP53INP1: 94,925,972–94,949,400, reverse strandTP53INP1PLEKHF2: 95,115,642–95,156,698, forward strandPLEKHF2Diagram of ESRP1: 16 exons on the forward strand of chromosome 8Exon 3: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 1: 94,641,174–94,641,450, 277 basesExon 2: 94,641,956–94,642,084, 129 basesExon 3: 94,643,303–94,643,416, 114 basesExon 4: 94,646,168–94,646,282, 115 basesExon 5: 94,662,272–94,662,370, 99 basesExon 6: 94,662,501–94,662,555, 55 basesExon 7: 94,664,697–94,664,807, 111 basesExon 8: 94,664,927–94,665,059, 133 basesExon 9: 94,665,154–94,665,196, 43 basesExon 10: 94,667,949–94,668,250, 302 basesExon 11: 94,671,453–94,671,671, 219 basesExon 12: 94,674,308–94,674,506, 199 basesExon 13: 94,678,203–94,678,371, 169 basesExon 14: 94,692,677–94,692,827, 151 basesExon 15: 94,696,852–94,696,961, 110 basesExon 16: 94,705,925–94,707,466, 1,542 bases151015165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.8 kb of the gene's 66.3 kb; 2,046 of those bases code for the protein.

How a genome test reads ESRP1

3

positions in ESRP1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 66.3 kb of ESRP1, introns included, not only the 3.8 kb of exons.

Traits linked to ESRP1

The Human Phenotype Ontology lists these as features of the rare conditions ESRP1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ESRP1 gene: epithelial splicing regulatory protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/esrp1

Vancouver

Dante Labs. ESRP1 gene: epithelial splicing regulatory protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/esrp1

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