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Gene

PLEKHF2

pleckstrin homology and FYVE domain containing 2

Summary

Cytogenetic location
8q22.1
Coordinates
Chromosome 8: 95,133,785–95,156,685 (GRCh38)
Exons
2 exons across 22.9 kb
Protein
249 amino acids
Also known as
ZFYVE18, PHAFIN2, FLJ13187
MANE Select transcript
ENST00000315367.4NM_024613.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PLEKHF2 yet. The test sequences your whole genome, so your data includes it all the same.

How PLEKHF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where PLEKHF2 sits. PLEKHF2 and 7 genes near it on chromosome 8, from 94,645,235 to 95,645,234.Chromosome 88q22.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.394.8 Mb95 Mb95.2 Mb95.4 Mb95.6 MbESRP1: 94,640,489–94,707,466, forward strandESRP1DPY19L4: 94,719,677–94,793,836, forward strandDPY19L4INTS8: 94,813,311–94,881,746, forward strandINTS8CCNE2: 94,874,347–94,896,680, reverse strandCCNE2NDUFAF6: 94,895,533–95,116,455, forward strandNDUFAF6TP53INP1: 94,925,972–94,949,400, reverse strandTP53INP1PLEKHF2: 95,133,785–95,156,685, forward strandPLEKHF2CFAP418: 95,243,176–95,269,430, reverse strandCFAP418Diagram of PLEKHF2: 2 exons on the forward strand of chromosome 8Exon 1: 95,133,785–95,134,030, 246 basesExon 2: 95,154,031–95,156,685, 2,655 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 22.9 kb; 750 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PLEKHF2 gene: pleckstrin homology and FYVE domain containing 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/plekhf2

Vancouver

Dante Labs. PLEKHF2 gene: pleckstrin homology and FYVE domain containing 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plekhf2

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