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Gene

INTS8

integrator complex subunit 8

Summary

Cytogenetic location
8q22.1
Coordinates
Chromosome 8: 94,823,287–94,881,746 (GRCh38)
Exons
27 exons across 58.5 kb
Protein
995 amino acids
Also known as
FLJ20530, INT8, MGC131633
Previous symbols
C8orf52
MANE Select transcript
ENST00000523731.6NM_017864.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads INTS8 yet. The test sequences your whole genome, so your data includes it all the same.

How INTS8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 8, with a bracket where INTS8 sits. INTS8 and 10 genes near it on chromosome 8, from 94,352,517 to 95,352,516.Chromosome 88q22.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.394.4 Mb94.6 Mb94.8 Mb95 Mb95.2 MbRAD54B: 94,371,960–94,475,134, reverse strandRAD54BFSBP: 94,378,377–94,436,952, reverse strandFSBPVIRMA: 94,487,689–94,553,529, reverse strandVIRMAESRP1: 94,640,489–94,707,466, forward strandESRP1DPY19L4: 94,719,677–94,793,836, forward strandDPY19L4INTS8: 94,823,287–94,881,746, forward strandINTS8CCNE2: 94,874,347–94,896,680, reverse strandCCNE2NDUFAF6: 94,895,533–95,116,455, forward strandNDUFAF6TP53INP1: 94,925,972–94,949,400, reverse strandTP53INP1PLEKHF2: 95,115,642–95,156,698, forward strandPLEKHF2CFAP418: 95,243,176–95,269,430, reverse strandCFAP418Diagram of INTS8: 27 exons on the forward strand of chromosome 8Exon 9: 1 known disease-causing siteExon 1: 94,823,287–94,823,561, 275 basesExon 2: 94,824,893–94,825,067, 175 basesExon 3: 94,827,263–94,827,403, 141 basesExon 4: 94,827,722–94,827,793, 72 basesExon 5: 94,828,975–94,829,026, 52 basesExon 6: 94,831,992–94,832,174, 183 basesExon 7: 94,836,524–94,836,631, 108 basesExon 8: 94,838,463–94,838,618, 156 basesExon 9: 94,841,491–94,841,591, 101 basesExon 10: 94,842,347–94,842,488, 142 basesExon 11: 94,849,462–94,849,532, 71 basesExon 12: 94,849,916–94,850,091, 176 basesExon 13: 94,851,553–94,851,686, 134 basesExon 14: 94,853,805–94,853,915, 111 basesExon 15: 94,856,777–94,856,978, 202 basesExon 16: 94,859,511–94,859,632, 122 basesExon 17: 94,865,506–94,865,690, 185 basesExon 18: 94,866,158–94,866,191, 34 basesExon 19: 94,867,140–94,867,196, 57 basesExon 20: 94,867,276–94,867,337, 62 basesExon 21: 94,871,884–94,872,002, 119 basesExon 22: 94,873,374–94,873,477, 104 basesExon 23: 94,874,552–94,874,602, 51 basesExon 24: 94,876,074–94,876,147, 74 basesExon 25: 94,876,221–94,876,285, 65 basesExon 26: 94,876,446–94,876,489, 44 basesExon 27: 94,880,118–94,881,746, 1,629 bases1510152025275′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.6 kb of the gene's 58.5 kb; 2,988 of those bases code for the protein.

How a genome test reads INTS8

1

position in INTS8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 58.5 kb of INTS8, introns included, not only the 4.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). INTS8 gene: integrator complex subunit 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/ints8

Vancouver

Dante Labs. INTS8 gene: integrator complex subunit 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ints8

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