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Gene

DOCK3

dedicator of cytokinesis 3

Summary

Cytogenetic location
3p21.2
Coordinates
Chromosome 3: 50,674,927–51,384,198 (GRCh38)
Exons
53 exons across 709.3 kb
Protein
2,030 amino acids
Also known as
KIAA0299, MOCA, PBP
MANE Select transcript
ENST00000266037.10NM_004947.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DOCK3 yet. The test sequences your whole genome, so your data includes it all the same.

How DOCK3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where DOCK3 sits. DOCK3 and 48 genes near it on chromosome 3, from 49,965,655 to 52,093,470.Chromosome 33p21.2p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2950 Mb50.5 Mb51 Mb51.5 Mb52 MbRBM6: 49,940,007–50,100,045, forward strandRBM6RBM5: 50,088,898–50,119,021, forward strandRBM5SEMA3F: 50,155,012–50,189,075, forward strandSEMA3FGNAT1: 50,191,586–50,197,696, forward strandGNAT1SLC38A3: 50,202,871–50,221,504, forward strandGNAI2: 50,226,292–50,259,362, forward strandSEMA3B: 50,267,507–50,277,573, forward strandLSMEM2: 50,279,030–50,288,116, forward strandIFRD2: 50,286,003–50,292,918, reverse strandHYAL3: 50,292,830–50,299,437, reverse strandNAA80: 50,296,402–50,299,437, reverse strandHYAL1: 50,299,883–50,312,890, reverse strandHYAL2: 50,313,396–50,324,687, reverse strandTUSC2: 50,320,027–50,328,251, reverse strandRASSF1: 50,329,782–50,340,980, reverse strandZMYND10: 50,341,110–50,345,746, reverse strandNPRL2: 50,347,330–50,350,826, reverse strandCYB561D2: 50,350,834–50,358,460, forward strandCYB561D2: 50,350,892–50,367,923, forward strandTMEM115: 50,352,820–50,359,566, reverse strandTMEM115CACNA2D2: 50,362,613–50,504,244, reverse strandCACNA2D2C3orf18: 50,556,409–50,573,568, reverse strandC3orf18HEMK1: 50,567,895–50,596,168, forward strandHEMK1CISH: 50,606,456–50,611,984, reverse strandCISHMAPKAPK3: 50,611,487–50,651,017, forward strandMAPKAPK3DOCK3: 50,674,927–51,384,198, forward strandDOCK3MANF: 51,385,255–51,389,802, forward strandMANFRBM15B: 51,391,285–51,397,908, forward strandRBM15BDCAF1: 51,395,867–51,500,097, reverse strandDCAF1RAD54L2: 51,538,666–51,668,667, forward strandRAD54L2TEX264: 51,662,693–51,704,323, forward strandTEX264GRM2: 51,707,057–51,718,616, forward strandGRM2IQCF6: 51,778,561–51,779,241, reverse strandIQCF6: 51,798,803–51,830,856, forward strandIQCF1: 51,809,295–51,903,369, reverse strandIQCF1IQCF3: 51,826,883–51,833,389, forward strandIQCF3IQCF2: 51,861,615–51,863,424, forward strandIQCF5: 51,873,721–51,875,601, reverse strandRRP9: 51,933,425–51,941,946, reverse strandRRP9PARP3: 51,942,252–51,949,371, forward strandPARP3GPR62: 51,955,381–51,957,499, forward strandGPR62PCBP4: 51,957,448–51,974,630, reverse strandABHD14B: 51,968,510–51,983,409, reverse strandABHD14A: 51,971,426–51,982,398, forward strandABHD14A-ACY1: 51,974,706–51,989,183, forward strandACY1: 51,983,047–51,989,457, forward strandRPL29: 51,993,522–51,996,021, reverse strandDUSP7: 52,048,919–52,056,577, reverse strandPOC1A: 52,074,590–52,154,746, reverse strandPOC1ADiagram of DOCK3: 53 exons on the forward strand of chromosome 3Exon 7: 1 known disease-causing siteExon 41: 2 known disease-causing sitesExon 53: 1 known disease-causing siteExon 1: 50,674,927–50,675,300, 374 basesExon 2: 50,778,675–50,778,758, 84 basesExon 3: 50,841,675–50,841,715, 41 basesExon 4: 50,890,026–50,890,081, 56 basesExon 5: 50,933,981–50,934,077, 97 basesExon 6: 51,064,448–51,064,596, 149 basesExon 7: 51,075,356–51,075,440, 85 basesExon 8: 51,089,243–51,089,284, 42 basesExon 9: 51,090,230–51,090,384, 155 basesExon 10: 51,146,549–51,146,630, 82 basesExon 11: 51,159,244–51,159,304, 61 basesExon 12: 51,160,555–51,160,702, 148 basesExon 13: 51,208,774–51,208,862, 89 basesExon 14: 51,214,122–51,214,247, 126 basesExon 15: 51,225,649–51,225,773, 125 basesExon 16: 51,227,283–51,227,445, 163 basesExon 17: 51,227,982–51,228,088, 107 basesExon 18: 51,228,661–51,228,832, 172 basesExon 19: 51,229,512–51,229,609, 98 basesExon 20: 51,236,345–51,236,428, 84 basesExon 21: 51,237,490–51,237,590, 101 basesExon 22: 51,246,726–51,246,807, 82 basesExon 23: 51,260,156–51,260,326, 171 basesExon 24: 51,270,815–51,271,007, 193 basesExon 25: 51,275,079–51,275,206, 128 basesExon 26: 51,277,608–51,277,754, 147 basesExon 27: 51,280,106–51,280,204, 99 basesExon 28: 51,310,232–51,310,326, 95 basesExon 29: 51,312,004–51,312,079, 76 basesExon 30: 51,312,476–51,312,576, 101 basesExon 31: 51,312,844–51,312,902, 59 basesExon 32: 51,314,980–51,315,128, 149 basesExon 33: 51,330,138–51,330,223, 86 basesExon 34: 51,333,001–51,333,027, 27 basesExon 35: 51,333,158–51,333,253, 96 basesExon 36: 51,338,359–51,338,419, 61 basesExon 37: 51,338,935–51,339,028, 94 basesExon 38: 51,341,237–51,341,385, 149 basesExon 39: 51,348,852–51,348,938, 87 basesExon 40: 51,350,288–51,350,392, 105 basesExon 41: 51,354,882–51,355,023, 142 basesExon 42: 51,356,089–51,356,255, 167 basesExon 43: 51,356,407–51,356,493, 87 basesExon 44: 51,356,962–51,357,141, 180 basesExon 45: 51,357,758–51,357,841, 84 basesExon 46: 51,357,961–51,358,077, 117 basesExon 47: 51,360,511–51,360,632, 122 basesExon 48: 51,361,859–51,361,997, 139 basesExon 49: 51,362,527–51,362,674, 148 basesExon 50: 51,374,469–51,374,587, 119 basesExon 51: 51,375,748–51,375,835, 88 basesExon 52: 51,380,125–51,380,207, 83 basesExon 53: 51,381,050–51,384,198, 3,149 bases12040535′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.1 kb of the gene's 709.3 kb; 6,093 of those bases code for the protein.

How a genome test reads DOCK3

5

positions in DOCK3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 709.3 kb of DOCK3, introns included, not only the 9.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DOCK3 gene: dedicator of cytokinesis 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/dock3

Vancouver

Dante Labs. DOCK3 gene: dedicator of cytokinesis 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/dock3

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