Traits

Traits linked to DNAL4

dynein axonemal light chain 4

The Human Phenotype Ontology links 14 traits to DNAL4, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

Trait	How often it is seen
Abnormal corticospinal tract morphology	Often (30–79%)
Abnormality of movement	Often (30–79%)
Clumsiness	Often (30–79%)
Hand mirror movements	Often (30–79%)
Poor fine motor coordination	Often (30–79%)
Agenesis of corpus callosum	Sometimes (5–29%)
Dysgenesis of the hippocampus	Sometimes (5–29%)
Specific learning disability	Sometimes (5–29%)
Cerebral palsy	Rarely (1–4%)
Intellectual disability, mild	Rarely (1–4%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Tired easily	Often (30–79%)
Fused neck	Rarely (1–4%)

Abnormality of the endocrine system

Trait	How often it is seen
Hypogonadotropic hypogonadism	Rarely (1–4%)

Constitutional symptom

Trait	How often it is seen
Muscle ache	Sometimes (5–29%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to DNAL4 and how often each is seen. Find out more at hpo.jax.org.

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