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Gene

CD59

CD59 molecule (CD59 blood group)

Summary

Cytogenetic location
11p13
Coordinates
Chromosome 11: 33,703,010–33,736,423 (GRCh38)
Exons
4 exons across 33.4 kb
Protein
128 amino acids
Also known as
16.3A5, EJ16, EJ30, EL32, G344, p18-20
Previous symbols
MIC11, MIN1, MSK21, MIN2, MIN3, MIRL, MACIF, HRF20
MANE Select transcript
ENST00000642928.2NM_000611.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CD59 yet. The test sequences your whole genome, so your data includes it all the same.

How CD59 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where CD59 sits. CD59 and 9 genes near it on chromosome 11, from 33,219,717 to 34,219,716.Chromosome 1111p13p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2533.4 Mb33.6 Mb33.8 Mb34 Mb34.2 MbHIPK3: 33,256,672–33,357,023, forward strandHIPK3KIAA1549L: 33,376,078–33,674,102, forward strandKIAA1549L: 33,698,261–33,722,467, reverse strandC11orf91: 33,698,261–33,700,826, reverse strandC11orf91CD59: 33,703,010–33,736,423, reverse strandCD59FBXO3: 33,739,834–33,774,543, reverse strandFBXO3LMO2: 33,858,563–33,892,076, reverse strandLMO2CAPRIN1: 34,051,649–34,103,835, forward strandCAPRIN1NAT10: 34,105,583–34,147,670, forward strandNAT10ABTB2: 34,150,987–34,358,043, reverse strandABTB2Diagram of CD59: 4 exons on the reverse strand of chromosome 11Exon 4: 3 known disease-causing sitesExon 3: 3 known disease-causing sitesExon 2: 1 known disease-causing siteExon 4: 33,703,010–33,710,343, 7,334 basesExon 3: 33,717,370–33,717,471, 102 basesExon 2: 33,722,379–33,722,463, 85 basesExon 1: 33,736,382–33,736,423, 42 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.6 kb of the gene's 33.4 kb; 387 of those bases code for the protein.

How a genome test reads CD59

7

positions in CD59 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 33.4 kb of CD59, introns included, not only the 7.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CD59 gene: CD59 molecule (CD59 blood group). Retrieved 17 October 2026, from https://dantelabs.com/genes/cd59

Vancouver

Dante Labs. CD59 gene: CD59 molecule (CD59 blood group) [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cd59

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