Traits

Traits linked to ATOH7

atonal bHLH transcription factor 7

The Human Phenotype Ontology links 33 traits to ATOH7, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the eye

Trait	How often it is seen
Inward turning cross eyed	Always
Leukocoria	Always
Remnants of the hyaloid vascular system	Always
Ultra-low vision with no light perception	Always
Abnormally small eyeball	Very often (80–99%)
Clouding of the lens of the eye	Very often (80–99%)
Corneal opacity	Very often (80–99%)
Decreased clarity of vision	Very often (80–99%)
Angle closure glaucoma	Often (30–79%)
Clouding of the lens of the eye at birth	Often (30–79%)
Glial remnants anterior to the optic disc	Often (30–79%)
Hyaloid vascular remnant and retrolental mass	Often (30–79%)
Persistent pupillary membrane	Often (30–79%)
Tractional retinal detachment	Often (30–79%)
Blindness	Sometimes (5–29%)
Cat eye	Sometimes (5–29%)
Cornea of eye less than 10mm in diameter	Sometimes (5–29%)
Cross-eyed	Sometimes (5–29%)
Enlarged eyeball	Sometimes (5–29%)
Increased tears	Sometimes (5–29%)
Lazy eye	Sometimes (5–29%)
Macular hypoplasia	Sometimes (5–29%)
Phthisis bulbi	Sometimes (5–29%)
Retinal fold	Sometimes (5–29%)
Shallow anterior chamber	Sometimes (5–29%)
Uveitis	Sometimes (5–29%)
Glaucoma	Not recorded
Pendular nystagmus	Not recorded
Posterior synechiae of the anterior chamber	Not recorded
Retinal nonattachment	Not recorded

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Bleeding from the eye	Sometimes (5–29%)
Hyphema	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Ectopic calcification	Rarely (1–4%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to ATOH7 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test