Skip to content
HSA/FSA eligible. CLIA/CAP laboratory. Results in 6-8 weeks

Risk score · Heart & circulation

Stroke Polygenic Risk Score

A stroke happens when blood supply to part of the brain is cut off or a vessel bleeds. Blood pressure, smoking and activity matter most, and genetics adds to them.

A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.

Updated 16 October 2026

Included in Premium and Premium + AI

Free shipping · Results in 6–8 weeks

Get my Stroke report

A polygenic score for Stroke

Genetic variants

90

Method

Clumping and Thresholding (C+T)

Built from studies of

European 100%

Evaluated in

European 100%

Published

Rutten-Jacobs LC et al. (2018). Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. BMJ.

The score in the PGS Catalog →

References

  1. Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, 2018. Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nat Genet

Other heart & circulation risk scores

All conditions →

One test. A lifetime of answers.

One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. Physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances.

Get my Stroke report

Free shipping · Results in 6–8 weeks