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Risk score · Heart & circulation

LDL Cholesterol Polygenic Score

Your genetic tendency towards higher or lower LDL ("bad") cholesterol, which builds up in artery walls. The score was built from a multi-ancestry study of 1.6 million people.

A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.

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A polygenic score for LDL cholesterol

Genetic variants

9,009

Method

Pruning and Thresholding (P+T)

Built from studies of

Multi-ancestry 100%

Evaluated in

African 55%, European 15%, East Asian 10%, Hispanic or Latin American 5%, Asian 5%, Multi-ancestry 5%, South Asian 5%

Published

Graham SE et al. (2021). The power of genetic diversity in genome-wide association studies of lipids. Nature.

The score in the PGS Catalog →

Other heart & circulation risk scores

All conditions →

One test. A lifetime of answers.

One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. Physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances.

From $449

Free shipping · Results in 6–8 weeks

Premium adds $99 per kit for the first year.

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