Risk score · Cancer
Colorectal Cancer Polygenic Risk Score
Colorectal cancer affects the colon or rectum and is one of the most common cancers worldwide. Screening can find it early, and family history and genetics both add to risk.
A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.
A polygenic score for Colorectal cancer
Genetic variants
- 76
Method
- Known susceptibility variants (genome-wide significant SNPs)
Built from studies of
- European 91%, African 9%
Evaluated in
- East Asian 67%, European 33%
Published
Schmit SL et al. (2019). Novel Common Genetic Susceptibility Loci for Colorectal Cancer. J Natl Cancer Inst.
Other cancer risk scores
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