Trait

Eye floaters

Clinical name: Vitreous floaters

Deposits of various size, shape, consistency, refractive index, and motility within the eye's vitreous humor, which is normally transparent.

HPO HP:0100832

Also called: Spots in front of eyes, Flitting flies, Mouches volantes, Myodeopsia, Myodesopsia, Vitreous condensations, Vitreous debris, Vitreous opacities, Vitreous veils
Body system: Abnormality of the eye

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13 genes linked to Eye floaters

Changes in these genes cause rare conditions in which Eye floaters is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
GON4Lgon-4 like	Always	In 1 condition
ARL3ARF like GTPase 3	Often (30–79%)	In 1 condition
ARSKarylsulfatase family member K	Often (30–79%)	In 1 condition
FZD4frizzled class receptor 4	Often (30–79%)	In 2 conditions
HLA-Amajor histocompatibility complex, class I, A	Often (30–79%)	In 1 condition
LRP5LDL receptor related protein 5	Often (30–79%)	In 2 conditions
P3H2prolyl 3-hydroxylase 2	Often (30–79%)	In 1 condition
PAK2p21 (RAC1) activated kinase 2	Often (30–79%)	In 1 condition
TTRtransthyretin	Often (30–79%)	In 1 condition
CTNNB1catenin beta 1	Sometimes (5–29%)	In 1 condition
NDPnorrin cystine knot growth factor NDP	Sometimes (5–29%)	In 1 condition
TSPAN12tetraspanin 12	Sometimes (5–29%)	In 1 condition
ZNF408zinc finger protein 408	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal vitreous humor morphology Entoptic phenomenon

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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